Voltammetric detection of nanomolar levels of hypoxanthine in the presence of copper (II) at glassy carbon electrode

Nanomolar levels of the hypoxanthine in NaOH electrolyte containing copper (II) can be determined by anodic stripping voltammetry at a glassy carbon electrode. In the present article hypoxanthine-Cu+ is shown to be adsorbed on the electrode surface in the presence of an excess of copper (II). After accumulation period, hypoxanthine-Cu+ was stripped from the electrode surface and the anodic current coming near to the oxidation of Cu(I) to Cu(II) was measured. A linear calibration curve in the range of 5 nmol/L-1.5 nmol/L hypoxanthine, with a detection limit of 0.5 nmol/L hypoxanthine were obtained.