Predictors and in-hospital prognosis of recurrent acute myocardial infarction

Objective To investigate the contributing factors and in-hospital prognosis of patients with or without recurrent acute myocardial infarction(AMI).Methods A total of 1686 consecutive AMI patients admitted to Peking University People's Hospital from January 2010 to December 2015 were recruited.Their clinical characteristics were retrospectively compared between patients with or without a recurrent AMI.Then multivariable logistic regression was used to estimate the predictors of recurrent myocardial infarction.Results Recurrent AMI patients were older(69.3 ± 11.5 vs.64.7 ± 12.8 years,P< 0.001) and had a higher prevalence of diabetes mellitus(DM)(52.2%vs.35.0%,P< 0.001) compared with incident AMI patients,they also had worse heart function at admission,more severe coronary disease and lower reperfusion therapy.Age(OR = 1.03,95%CI:1.02-1.05;P < 0.001),DM(OR = 1.86,95%CI:1.37-2.52;P < 0.001) and reperfusion therapy(OR = 0.74;95%CI:0.52-0.89;P < 0.001) were independent risk factors for recurrent AMI.Recurrent AMI patients had a higher in-hospital death rate(12.1%vs.7.8%),P = 0.039) than incident AMI patients.Conclusions Recurrent AMI patients presented with more severe coronary artery conditions.Age,DM and reperfusion therapy were independent risk factors for recurrent AMI,and recurrent AMI was related with a high risk of in-hospital death.