A dual-targeted trinity of antibody-peptide-drug delivery consortium to combat HER2+tumor

被引：0
|
作者：
Shang, Yuna [1 ]
Wang, Jiayu [1 ]
Feng, Yinyin [1 ]
Liu, Zhengyu [1 ]
Lu, Jiayi [1 ]
Deng, Sijia [4 ]
Li, Li [1 ]
Zhang, Hongxu [1 ]
Li, Liantao [4 ]
Wang, Zhongyan [3 ]
Yang, Zhimou [2 ,4 ]
机构：
[1] Tianjin Normal Univ, Acad Interdisciplinary Studies Intelligent Mol, Coll Chem, Tianjin Key Lab Struct & Performance Funct Mol, Tianjin 300387, Peoples R China
[2] Wenzhou Med Univ, Affiliated Hosp 1, Zhejiang Key Lab Intelligent Canc Biomarker Discov, Wenzhou 325035, Zhejiang, Peoples R China
[3] Chinese Acad Med Sci & Peking Union Med Coll, Tianjin Inst Hlth Sci, Inst Radiat Med, State Key Lab Adv Med Mat & Devices,Tianjin Key La, Tianjin 300192, Peoples R China
[4] Xuzhou Med Univ, Affiliated Hosp, Ctr Clin Oncol, Jiangsu Ctr Collaborat & Innovat Canc Biotherapy, Xuzhou 221004, Jiangsu, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 93期
基金：
中国国家自然科学基金;
关键词：
Self assembly;
D O I：
10.1039/d4cc05115g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We pioneered a dual-targeted trinity of antibody-peptide-drug delivery consortium to combat HER2+ tumors. This innovative approach leverages the self-assembly of peptides with high affinity to antibodies to create nanofibers for antibody encapsulation, offering a novel strategy in antibody drug delivery.
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收藏
页码：13742 / 13745
页数：4
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