Isolation of a novel antifungal peptide from the bark of Eucommia ulmoides Oliv

被引：0
|
作者：
Liu, Shihui [1 ,2 ]
Zhao, Degang [1 ,2 ]
Han, Yuzhen [3 ]
机构：
[1] Guizhou Key Laboratory of Agricultural Bioengineering, College of Life Sciences, Guizhou University, Guiyang 550025, China
[2] Key Lab. of Green Pesticide and Agricultural Biological Engineering, Guizhou University, Guiyang 550025, China
[3] College of Biological Sciences, China Agricultural University, Beijing 100094, China
来源：
High Technology Letters | 2008年 / 14卷 / 02期
关键词：
Antifungal peptide - Bark of Eucommia ulmoides Oliv - Candida albicans - Gel filtration - Growth inhibition - Inhibitory activity - Isolation - Reverse phase high performance liquid chromatography;
D O I：
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中图分类号：
学科分类号：
摘要：
A novel Eucommia antifungal peptide, named EAFP3, was isolated from the bark of Eucommia ulmoides by NaCl extract, gel filtration and reverse phase high performance liquid chromatography. The molecular mass of EAFP3 is 4157.3 Da, and its partial amino acid sequence is -. LYQQLIAGITLNK. -. EAFP3 exerts an inhibitory activity against Candida albicans in vitro and the drug concentration required for 50% growth inhibition (IC50) is 31.25 μg/mL.
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页码：216 / 219
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