Synthesis of carbohydrate-conjugated furo[2,3-d]pyrimidine by 'Click Chemistry'

被引:0
|
作者
Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, China [1 ]
不详 [2 ]
机构
关键词
Carbohydrates - Nitrogen compounds - Spectroscopy;
D O I
10.1055/s-2008-1032191
中图分类号
学科分类号
摘要
Compounds belonging to a new type of furo[2,3-d]pyrimidine nucleoside conjugated with carbohydrate were synthesized by Sonogashira coupling and 'click chemistry'. Their structures were confirmed on the basis of various types of spectroscopy. © Georg Thieme Verlag Stuttgart.
引用
收藏
相关论文
共 50 条
  • [21] Synthesis and molluscicidal activity of some new substituted-furan and furo[2,3-d]pyrimidine derivatives
    Abdelrazek, Fathy M.
    Michael, Farid A.
    El-Mahrouky, Sherif F.
    INTERNATIONAL JOURNAL OF THE PHYSICAL SCIENCES, 2007, 2 (08): : 212 - 216
  • [22] Furo[2,3-d]pyrimidine based derivatives as kinase inhibitors and anticancer agents
    Aziz, Marwa A.
    Serya, Rabah A. T.
    Lasheen, Deena S.
    Abouzid, Khaled A. M.
    FUTURE JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 2 (01) : 1 - 8
  • [23] Efficient synthesis of novel furo[2,3-d]pyrimidine derivatives under catalyst-free conditions
    Li, Chunmei
    Zhang, Furen
    TETRAHEDRON LETTERS, 2017, 58 (16) : 1572 - 1575
  • [24] Stereoselective synthesis of medicinally relevant furo[2,3-d]pyrimidine framework by thermal rearrangement of spirocyclic barbiturates
    Vereshchagin, Anatoly N.
    Elinson, Michail N.
    Dorofeeva, Evgeniya O.
    Sokolova, Olga O.
    Bushmarinov, Ivan S.
    Egorov, Michail P.
    RSC ADVANCES, 2015, 5 (115) : 94986 - 94989
  • [25] Efficient synthesis and biological evaluation of some 2,4-diamino-furo[2,3-d]pyrimidine derivatives
    Hu, Yang-Gen
    Wang, Yan
    Du, Shi-Ming
    Chen, Xiao-Bao
    Ding, Ming-Wu
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (21) : 6188 - 6190
  • [26] Synthesis, Cytostatic and Antibacterial Evaluations of Novel 1,2,3-Triazolyl-tagged Pyrimidine and Furo[2,3-d] pyrimidine Derivatives
    Babic, Maja Stipkovic
    Ratkovic, Ana
    Jukic, Marijana
    Glavas-Obrovac, Ljubica
    Drenjancevic, Domagoj
    Raic-Malic, Silvana
    Kraljevic, Tatjana Gazivoda
    CROATICA CHEMICA ACTA, 2017, 90 (02) : 197 - 205
  • [27] Synthesis of carbohydrate-conjugated nanoparticles and quantum dots
    Earhart, Christopher
    Jana, Nikhil R.
    Erathodiyil, Nandanan
    Ying, Jackie Y.
    LANGMUIR, 2008, 24 (12) : 6215 - 6219
  • [28] Synthesis of carbohydrate-conjugated azaphthalocyanine complexes for PDT
    Park, Jong Min
    Song, Cheol Jun
    Yao, Wang
    Jung, Chang Young
    Hyun, In Ho
    Seong, Dong Hoon
    Jaung, Jae Yun
    TETRAHEDRON LETTERS, 2015, 56 (35) : 4967 - 4970
  • [29] Synthesis and evaluation of a classical 2,4-diamino-5-substituted-furo[2,3-d]pyrimidine and a 2-amino-4-oxo-6-substituted-pyrrolo[2,3-d]pyrimidine as antifolates
    Gangjee, Aleem
    Yang, Jie
    McGuire, John J.
    Kisliuk, Roy L.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (24) : 8590 - 8598
  • [30] Synthesis and antifolate activity of new pyrrolo[2,3-d]pyrimidine and thieno[2,3-d]pyrimidine inhibitors of dihydrofolate reductase
    Vaidya, C
    Wright, JE
    Rosowsky, A
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2004, 41 (05) : 787 - 793