Evaluating Laser-Based Microfabrication in Microfluidics: An Experimental and Computational Trial

被引：0

作者：

Betti, Alice ^{[1
]}

Ongaro, Claudio ^{[1
]}

Zardin, Barbara ^{[1
]}

Bertacchini, Jessika ^{[2
]}

Tagliaferri, Nadia ^{[2
]}

Siciliani, Vincenzina ^{[3
]}

Orazi, Leonardo ^{[3
]}

Borghi, Massimo ^{[1
]}

机构：

[1] Engineering Department Enzo Ferrari DIEF, University of Modena and Reggio Emilia, via P. Vivarelli 10, Modena,41125, Italy

[2] Department of Surgery, Medicine, Dentistry and Morphological Sciences with Interest in Transplant, Oncology and Regenerative Medicine, CHIMOMO, via del Pozzo 71, Modena,41125, Italy

[3] Department of Sciences and Methods for Engineering DISMI, University of Modena and Reggio Emilia, via Amendola 2, Pad. Morselli, Reggio Emilia,42122, Italy

来源：

Advanced Engineering Materials | 2024年 / 26卷 / 21期

关键词：

Fluidic devices - Microfabrication;

D O I：

10.1002/adem.202401105

中图分类号：

学科分类号：

摘要：

The aim of this research is to validate a new prototyping method for microfluidic devices which could compete with the widely used polydimethylsiloxane soft lithography. This alternative methodology uses laser-etched glass and pre-cured silicone as main materials. A dual approach is chosen for validation, testing prototypes of a mixing device well known in the scientific literature. Specifically the focus is to evaluate the mixing efficiency (ME) of two fluids flowing through the device. After fine-tuning the fabrication process, the ME is experimentally evaluated, and the results are compared with a 3D computational fluid dynamic analysis. © 2024 The Author(s). Advanced Engineering Materials published by Wiley-VCH GmbH.

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