Direct acylation of aryl bromides with aldehydes by palladium catalysis

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Ruan, Jiwu [1 ]
Saidi, Ourida [1 ]
Iggo, Jonathan A. [1 ]
Xiao, Jianliang [1 ]
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[1] Department of Chemistry, Liverpool Centre for Materials and Catalysis, University of Liverpool, Liverpool L69 7ZD, United Kingdom
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A new protocol for the direct acylation of aryl bromides with aldehydes is established. It appears to involve palladium-amine cooperative catalysis; affording synthetically important alkyl aryl ketones in moderate to excellent yields in a straightforward manner; and broadening the scope of metal-catalyzed coupling reactions. Copyright © 2008 American Chemical Society;
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页码:10510 / 10511
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