Water-soluble chitosan graft polymers

被引：0
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作者：
The Petroleum and Petrochemical College, Chulalongkorn University, Phya Thai, Bangkok 10330, Thailand [1 ]
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来源：
Ind Bioprocess | 2006年 / 4卷 / 08期
关键词：
Ethers - Polyethylene glycols - Temperature - Water;
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摘要：
Researchers at Chulalongkorn University, Thailand used a one-pot-aqueous-phase process to produce water-soluble chitosan-graft-poly(ethylene glycol) methyl ether. The poly(ethylene glycol) methyl ether (mPEG) attaches to the chitosan at the amino and hydroxyl groups in a single step reaction. The mPEG reacts with chitosan and hydroxybenzotriazole in water, using a carbodiimide conjugating agent. The reaction proceeds at ambient temperature of 24 h. The water soluble product contains as much as 42% mPEG. The process does not require acids or organic solvents.
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