A comprehensive review of non-invasive optical and microwave biosensors for glucose monitoring

被引:0
|
作者
Martins, Ana J. L. [1 ]
Velasquez, Reinaldo J. [1 ]
Gaillac, Denis B. [1 ]
Santos, Vanessa N. [2 ]
Tami, Diego C. [3 ]
Souza, Rodrigo N. P. [4 ]
Osorio, Fernan C. [5 ]
Fogli, Gabriel A. [1 ,2 ]
Soares, Beatriz S. [4 ,6 ]
do Rego, Cassio G. [1 ,2 ]
Medeiros-Ribeiro, Gilberto [1 ,7 ]
Drummond, Juliana B. [4 ]
Mosquera-Lopez, Clara M. [8 ]
Ramirez, Jhonattan C. [1 ,2 ]
机构
[1] Univ Fed Minas Gerais, Programa Posgrad Engn Elect, BR-31270901 Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais, Dept Engn Eletroen, BR-31270901 Belo Horizonte, MG, Brazil
[3] Univ Fed Itajuba, Inst Cieencias Tecnol, BR-35903087 Itabira, MG, Brazil
[4] Univ Fed Minas Gerais, Hosp Clin, Serv Endocrinol & Metabol, BR-30130100 Belo Horizonte, MG, Brazil
[5] Univ Catolica Pereira, Fac Ciencias Bas Ingn, Pereira, Risaralda, Colombia
[6] Univ Fed Minas Gerais, Fac Med, Dept Clin Med, BR-30130100 Belo Horizonte, MG, Brazil
[7] Univ Fed Minas Gerais, Dept Cieencia Computacao, BR-31270901 Belo Horizonte, MG, Brazil
[8] Oregon Hlth & Sci Univ, Dept Biomed Engn, Portland, OR 97239 USA
来源
BIOSENSORS & BIOELECTRONICS | 2025年 / 271卷
关键词
Non-invasive glucose monitoring; Optical glucose sensors; Microwave glucose sensors; Continuous glucose monitoring (CGM); Diabetes management technology; BLOOD-GLUCOSE; DIABETES MANAGEMENT; INSULIN DELIVERY; LEVEL; PERMITTIVITY; MULTICENTER; ADULTS; WATER;
D O I
10.1016/j.bios.2024.117081
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Frequent glucose monitoring is essential for effective diabetes management. Currently, glucose monitoring is done using invasive methods such as finger-pricking and subcutaneous sensing. However, these methods can cause discomfort, heighten the risk of infection, and some sensing devices need frequent calibration. Noninvasive glucose monitoring technologies have attracted significant attention due to their potential to overcome the limitations of their invasive counterparts by offering painless and convenient alternatives. This review focuses on two prominent approaches to non-invasive glucose sensing: optical- and microwave-based methods. On one hand, optical techniques, including Raman and near-infrared (NIR) spectroscopy, leverage the unique spectral properties of glucose molecules to measure their concentration in tissues and biofluids. On the other hand, microwave sensing leverages the dielectric properties of glucose to detect concentration changes based on impedance measurements. Despite their promise, optical- and microwave-based technologies face challenges such as signal interference and high variability due to tissue heterogeneity, which impact their accuracy and reliability. This review provides a comprehensive overview of the advancements of these non-invasive methods, highlighting their technical implementation, limitations, and their future potential in revolutionizing glucose monitoring for diabetes care.
引用
收藏
页数:13
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