Research optical interferometer biosensor based on porous silicon

被引：0
|
作者：
Li, Rui [1 ]
Tu, Yi-Xian [4 ]
Li, Chen-Chen [4 ]
Lv, Xiao-Yi [2 ]
Jia, Zhen-Hong [3 ]
Zhang, Fu-Chun [4 ]
机构：
[1] School of Physics, Xinjiang University, Urumqi 830046, China
[2] School of Electronic and Information Engineer, Xi'an Jiaotong University, Xi'an 710049, China
[3] College of Information Science and Engineering, Xinjiang University, Urumqi 830046, China
[4] Key Laboratory of Xinjiang Biological Resources and Gene Engineering, College of Life Sciences and Technology, Xinjiang University, Urumqi 830046, China
来源：
Guangdianzi Jiguang/Journal of Optoelectronics Laser | 2010年 / 21卷 / 07期
关键词：
Biosensors - Doppler effect - Antibodies - Antigens - Fourier transforms - Silicon compounds;
D O I：
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中图分类号：
学科分类号：
摘要：
The micro-porous silicon is prepared as sensor support material, and the Si-OH band at the surface is formed by the immersion method of hydrogen peroxide. Porous silicon is functionalized by using oxidation and silanization, then Ang-II antibody with different concentration are immobilized to the porous surface by glutaraldehyde. The changes of Fourier transformation infrared spectrum and reflect spectrum before and after antigen-antibody reaction are observed. The results show that silanization effect is obvious. After antigen-antibody reaction, the reflection spectrum has a red shift, and the red shift of spectrum increases with the increase of antibody concentration, and presents a nonlinear relationship.
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页码：1111 / 1114
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