Iron (II) catalyzed cyclization of ketoxime acetates with triethyl orthoformate: An easy access to symmetrical pyridines

被引：0

作者：

Satishkumar, Kotyada ^{[1
]}

Lakshmi, Podugu Rajitha ^{[1
]}

Kumari, Yettula ^{[1
]}

Christopher, Voosala ^{[1
]}

Siddaiah, Vidavalur ^{[1
]}

机构：

[1] Andhra Univ, Dept Chem, Visakhapatnam 530003, India

来源：

SYNTHETIC COMMUNICATIONS | 2024年 / 54卷 / 23期

关键词：

Symmetrical pyridines; ketoxime acetates; triethyl orthoformate; FeCl2; N-O bond cleavage; C1 carbon source; OXIME ACETATES; ANNULATION; COPPER;

D O I：

10.1080/00397911.2024.2421364

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient iron (II) catalyzed approach to the synthesis of symmetrical pyridines has been demonstrated using ketoxime acetates and triethyl orthoformate in DMF at 120 degrees C under nitrogen environment. In this strategy, significantly, triethyl orthoformate functions as C1 carbon source and which is noteworthy. Other benefits of this process include good yields, high functional group tolerance, low cost of catalyst and avoiding of use of hazardous chemicals.

引用

页码：2064 / 2075

页数：12

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