Resonant Waveguide Grating Biosensors Based on Label-free Optical Principle

被引：0
|
作者：
Sallai I. [1 ]
机构：
[1] Nanobiosensorics Laboratory, Center of Energy Research, Eötvös Loránd Research Network, Konkoly-Thege Miklós út 29–33., Budapest
来源：
Periodica polytechnica Electrical engineering and computer science | 2024年 / 68卷 / 01期
关键词：
evanescent field; molecular interactions; waveguide grating;
D O I：
10.3311/PPee.22878
中图分类号：
学科分类号：
摘要：
Label-free optical biosensors are powerful tools for the real-time monitoring of both molecular and cellular-scale interactions. Resonant waveguide grating biosensors are based on the detection of refractive index changes induced by molecular interactions and/or cell mass redistributions. The Epic BenchTop and Epic Cardio are two biosensors with high sensitivity and throughput that offer excellent potential for life science research. Both instruments are suitable for cell-based and biochemical assays. In this paper, I describe the principles of operation and performance of the Epic BenchTop and Epic Cardio label-free waveguide grating biosensors and discuss their applications in various research areas. © 2024 Budapest University of Technology and Economics. All rights reserved.
引用
收藏
页码：107 / 114
页数：7
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