Reversal of Solvatochromism: A New Strategy to Construct Activatable Two-photon Fluorescent Probes for Sensing

被引：0
|
作者：
Zheng, Yingxin [1 ]
Zhang, Xing-Xing [1 ]
Shi, Ling [1 ]
Ren, Tian-Bing [1 ]
Yuan, Lin [1 ]
Zhang, Xiao-Bing [1 ]
机构：
[1] State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha,410082, China
来源：
Chemistry - An Asian Journal | 2022年 / 17卷 / 01期
关键词：
Charge transfer - Probes - Fluorescence - Photons;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two-photon (TP) imaging with a donor-acceptor (D−A) type fluorophore is an emerging tool for bioimaging and sensing. However, current TP probes suffer from serious solvatochromic quenching in aqueous solution due to their strong intramolecular charge transfer (ICT) in excited states. In this work, based on solvatochromism reversal, we report a novel strategy to develop TP probes for bioimaging. Specifically, compared with the normal two-photon probes that showed a fluorescence off with ICT suppressed, the novel probes exhibited strong fluorescence in the aqueous solution when their ICT was inhibited. This strategy not only provides a new way for the design of high-performance TP probes, but also expands the biological analysis toolbox for use in living systems. © 2021 Wiley-VCH GmbH
引用
收藏
相关论文
共 50 条
  • [21] Two-Photon Fluorescent Probes for Metal Ions in Live Tissues
    Sarkar, Avik Ranjan
    Kang, Dong Eun
    Kim, Hwan Myung
    Cho, Bong Rae
    INORGANIC CHEMISTRY, 2014, 53 (04) : 1794 - 1803
  • [22] Pluronic organic fluorescent probes for two-photon vascularisation imaging
    Maurin, Mathieu
    Vurth, Laetitia
    Vial, Jean-Claude
    Baldeck, Patrice
    Marder, Seth R.
    Van Der Sanden, Boudewijn
    Stéphan, Olivier
    Nonlinear Optics Quantum Optics, 2010, 40 (1-4): : 175 - 181
  • [23] Studies of new two-photon fluorescent probes suitable for multiphoton microscopy in biological settings
    Gvishi, R
    Berkovic, G
    Kotler, Z
    Krief, P
    Shapiro, L
    Klug, JT
    Skorka, J
    Khodorkovsky, V
    NONLINEAR OPTICAL TRANSMISSION AND MULTIPHOTON PROCESSES IN ORGANICS, 2003, 5211 : 82 - 90
  • [24] Theoretical insights into sensing performances of rhodamine-contained two-photon fluorescent probes for mercury ion
    Leng, Jiancai
    Xin, Juntao
    Zhou, Hong
    Li, Kan
    Hu, Wei
    Zhang, Yujin
    INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, 2021, 121 (02)
  • [25] Analyzing Nonmelanoma Skin Cancer Using Enzyme-Activatable Two-Photon Probes
    Lim, Chang Su
    Choi, Jee Woong
    Kim, You Chan
    Kim, Hwan Myung
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2021, 42 (01) : 103 - 106
  • [26] Two-Photon Fluorescent Probes for Amyloid-β Plaques Imaging In Vivo
    Chen, Yi
    MOLECULES, 2023, 28 (17):
  • [27] In silico design of two-photon fluorescent probes for detecting nitric oxide
    Liu, Xiaoting
    Zhang, Ji-Long
    INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY, 2023, 123 (13)
  • [28] Recent progress in two-photon small molecule fluorescent probes for enzymes
    Chen, Ding
    Qin, Wenjing
    Fang, Haixiao
    Wang, Lan
    Peng, Bo
    Li, Lin
    Huang, Wei
    CHINESE CHEMICAL LETTERS, 2019, 30 (10) : 1738 - 1744
  • [29] Two-Photon Fluorescent Probes for Detecting Enzyme Activities in Live Tissues
    Juvekar, Vinayak
    Lee, Hyo Won
    Kim, Hwan Myung
    ACS APPLIED BIO MATERIALS, 2021, 4 (04) : 2957 - 2973
  • [30] One-Photon and Two-Photon Mitochondrial Fluorescent Probes Based on a Rhodol Chromophore
    Poronik, Yevgen M.
    Bernas, Tytus
    Wrzosek, Antoni
    Banasiewicz, Marzena
    Szewczyk, Adam
    Gryko, Daniel T.
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2018, 7 (02) : 411 - 415
12345