A mild and convenient protocol for the synthesis of quinoxalin-2(1H)-ones and benzimidazoles

被引：0
|
作者：
Luo, Zhenbiao [1 ]
Wang, Mingyuan [1 ]
Jiang, Guidong [1 ]
Wang, Xinye [1 ]
Zhao, Liang [1 ]
Hu, Zhihui [1 ]
Li, Honghe [1 ]
Ji, Qing [1 ]
机构：
[1] Department of Brewing Engineering, Moutai Institute, Renhuai, Guizhou,564507, China
来源：
RSC Advances | 2024年 / 14卷 / 48期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1039/d4ra06887d
中图分类号：
O62 [有机化学]; TQ [化学工业];
学科分类号：
070303 ; 0817 ; 081704 ;
摘要：
We present a mild and simple method for the cyclization of N-protected o-phenylenediamines with carbonyl compounds in the presence of trifluoroacetic acid. This method reliably provides various substrates of benzimidazoles and quinoxalin-2(1H)-ones, with all reactions conducted at room temperature, demonstrating excellent substrate adaptability and a broad substrate scope. © 2024 The Royal Society of Chemistry.
引用
收藏
页码：35386 / 35390
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