Surfactant replacement options for Triton X-100 in bioprocessing

被引：0
|
作者：
Matte, Allan [1 ]
机构：
[1] Downstream Processing Team, Human Health Therapeutics Research Center, National Research Council, Canada
来源：
European Pharmaceutical Review | 2024年 / 29卷 / 03期
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The implementation of REACH regulations impacting use of Triton X-100 in bioprocessing within the EU is having an impact on sponsors and manufacturers as they look to detergent alternatives for their processes for new manufactured products. Drug developers in non-EU jurisdictions have also been following these changes and considering the overall risk environment and how to respond appropriately to these changes. The increased variety of REACH-compliant, high-quality detergents that can be tested for either cell lysis or adventitious virus reduction continues to grow, offering process developers of biologic drugs a variety of potential options, depending on the specific requirements of their process and product. © 2024 Russell Publishing. All rights reserved.
引用
收藏
页码：40 / 43
相关论文
共 50 条
  • [31] Degradation of Triton X-100 surfactant/lipid regulator systems by ionizing radiation in water
    Gergely Rácz
    Tamás Csay
    Erzsébet Takács
    László Wojnárovits
    [J]. Journal of Radioanalytical and Nuclear Chemistry, 2017, 314 : 1189 - 1196
  • [32] Adsorption of nonionic surfactant Triton X-100 on solids from aqueous and nonaqueous solutions
    Soboleva O.A.
    Badun G.A.
    Summ B.D.
    [J]. Moscow University Chemistry Bulletin, 2007, 62 (1) : 13 - 17
  • [33] WETTING IN THE SYSTEM POLYETHYLENE - AQUEOUS-SOLUTION OF NONIONIC SURFACTANT TRITON X-100
    BOGDANOVA, YG
    DOLZHIKOVA, VD
    SUMM, BD
    [J]. VESTNIK MOSKOVSKOGO UNIVERSITETA SERIYA 2 KHIMIYA, 1995, 36 (03): : 262 - 266
  • [34] Degradation of Triton X-100 surfactant/lipid regulator systems by ionizing radiation in water
    Racz, Gergely
    Csay, Tamas
    Takacs, Erzsebet
    Wojnarovits, Laszlo
    [J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 2017, 314 (02) : 1189 - 1196
  • [35] Effect of Surfactant (Triton X-100) Concentration on Dispersion and Functionalization of Multiwall Carbon Nanotubes
    Randhawa, Prabhsharan
    Park, Jin-Soo
    Sharma, Sandeep
    Kumar, Pawan
    Shin, Mun-Sik
    Sekhon, S. S.
    [J]. JOURNAL OF NANOELECTRONICS AND OPTOELECTRONICS, 2012, 7 (03) : 279 - 286
  • [36] Interaction of cephanone with Triton X-100 aggregates
    Zhu, J
    Qian, JH
    Guo, R
    [J]. ACTA PHYSICO-CHIMICA SINICA, 2005, 21 (03) : 234 - 238
  • [37] The removal of Triton X-100 by dialysis is feasible!
    Opitz, Stefan
    Hannika, Franziska
    Krueger, Thomas
    Rhode, Heidrun
    [J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2015, 407 (04) : 1107 - 1118
  • [38] TRITIUM COUNTING WITH TRITON X-100 SCINTILLANT
    TURNER, JC
    [J]. INTERNATIONAL JOURNAL OF APPLIED RADIATION AND ISOTOPES, 1969, 20 (07): : 499 - &
  • [39] Influence of Triton X-100 in stripping potentiometry
    Sahlin, E
    Jagner, D
    [J]. ANALYTICA CHIMICA ACTA, 1996, 333 (03) : 233 - 240
  • [40] Photobleaching of bacteriorhodopsin solubilized with Triton X-100
    Sasaki, T
    Sonoyama, M
    Demura, M
    Mitaku, S
    [J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2005, 81 (05) : 1131 - 1137
12345