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- [21] Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesisNATURE CHEMICAL BIOLOGY, 2012, 8 (10) : 839 - 847Anastasiou, Dimitrios论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA Harvard Univ, Sch Med, Dept Syst Biol, Boston, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAYu, Yimin论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAIsraelsen, William J.论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAJiang, Jian-Kang论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USABoxer, Matthew B.论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAHong, Bum Soo论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Struct Genom Consortium, Toronto, ON, Canada Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USATempel, Wolfram论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Struct Genom Consortium, Toronto, ON, Canada Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USADimov, Svetoslav论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Struct Genom Consortium, Toronto, ON, Canada Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAShen, Min论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAJha, Abhishek论文数: 0 引用数: 0 h-index: 0机构: MIT, Dept Chem Engn, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAYang, Hua论文数: 0 引用数: 0 h-index: 0机构: Agios Pharmaceut, Cambridge, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAMattaini, Katherine R.论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAMetallo, Christian M.论文数: 0 引用数: 0 h-index: 0机构: Univ Calif San Diego, Dept Bioengn, San Diego, CA 92103 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAFiske, Brian P.论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USACourtney, Kevin D.论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA Harvard Univ, Sch Med, Dept Syst Biol, Boston, MA USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAMalstrom, Scott论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAKhan, Tahsin M.论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAKung, Charles论文数: 0 引用数: 0 h-index: 0机构: Agios Pharmaceut, Cambridge, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USASkoumbourdis, Amanda P.论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAVeith, Henrike论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USASouthall, Noel论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAWalsh, Martin J.论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USABrimacombe, Kyle R.论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USALeister, William论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USALunt, Sophia Y.论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAJohnson, Zachary R.论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAYen, Katharine E.论文数: 0 引用数: 0 h-index: 0机构: Agios Pharmaceut, Cambridge, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAKunii, Kaiko论文数: 0 引用数: 0 h-index: 0机构: Agios Pharmaceut, Cambridge, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USADavidson, Shawn M.论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAChristofk, Heather R.论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAAustin, Christopher P.论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAInglese, James论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAHarris, Marian H.论文数: 0 引用数: 0 h-index: 0机构: Childrens Hosp, Dept Pathol, Boston, MA 02115 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAAsara, John M.论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA Harvard Univ, Sch Med, Dept Med, Boston, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAStephanopoulos, Gregory论文数: 0 引用数: 0 h-index: 0机构: MIT, Dept Chem Engn, Cambridge, MA 02139 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USASalituro, Francesco G.论文数: 0 引用数: 0 h-index: 0机构: Agios Pharmaceut, Cambridge, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAJin, Shengfang论文数: 0 引用数: 0 h-index: 0机构: Agios Pharmaceut, Cambridge, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USADang, Lenny论文数: 0 引用数: 0 h-index: 0机构: Agios Pharmaceut, Cambridge, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAAuld, Douglas S.论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAPark, Hee-Won论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Struct Genom Consortium, Toronto, ON, Canada Univ Toronto, Dept Pharmacol, Toronto, ON, Canada Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USACantley, Lewis C.论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA Harvard Univ, Sch Med, Dept Syst Biol, Boston, MA USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAThomas, Craig J.论文数: 0 引用数: 0 h-index: 0机构: Natl Ctr Adv Translat Sci, NIH, Chem Genom Ctr, Bethesda, MD USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USAHeiden, Matthew G. Vander论文数: 0 引用数: 0 h-index: 0机构: MIT, Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA Beth Israel Deaconess Med Ctr, Dept Med, Div Signal Transduct, Boston, MA 02215 USA
- [22] Discovery, development, and utility of activators of the human M2 isoform of pyruvate kinaseABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 242Thomas, Craig J.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USABoxer, Matthew B.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USAJiang, Jian-Kang论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USAVander Heiden, Matthew G.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA Harvard Univ, Sch Med, Dept Syst Biol, Cambridge, MA 02138 USA MIT, David H Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA Dana Farber Canc Inst, Boston, MA USAWalsh, Martin J.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USABrimacombe, Kyle论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USAShen, Min论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USASkoumbourdis, Amanda P.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USAPark, Hee Won论文数: 0 引用数: 0 h-index: 0机构: Univ Toronto, Struct Genom Consortium, Toronto, ON M5S 1A1, Canada Univ Toronto, Dept Pharmacol, Toronto, ON M5S 1A1, Canada Dana Farber Canc Inst, Boston, MA USACantley, Lewis C.论文数: 0 引用数: 0 h-index: 0机构: Harvard Univ, Sch Med, Dept Syst Biol, Cambridge, MA 02138 USA Beth Israel Deaconess Med Ctr, Div Signal Transduct, Boston, MA USA Dana Farber Canc Inst, Boston, MA USAAuld, Douglas S.论文数: 0 引用数: 0 h-index: 0机构: Dana Farber Canc Inst, Boston, MA USA
- [23] Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesisNature Chemical Biology, 2012, 8 : 839 - 847Dimitrios Anastasiou论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionYimin Yu论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionWilliam J Israelsen论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionJian-Kang Jiang论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionMatthew B Boxer论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionBum Soo Hong论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionWolfram Tempel论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionSvetoslav Dimov论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionMin Shen论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionAbhishek Jha论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionHua Yang论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionKatherine R Mattaini论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionChristian M Metallo论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionBrian P Fiske论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionKevin D Courtney论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionScott Malstrom论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionTahsin M Khan论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionCharles Kung论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionAmanda P Skoumbourdis论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionHenrike Veith论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionNoel Southall论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionMartin J Walsh论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionKyle R Brimacombe论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionWilliam Leister论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionSophia Y Lunt论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionZachary R Johnson论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionKatharine E Yen论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionKaiko Kunii论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionShawn M Davidson论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionHeather R Christofk论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionChristopher P Austin论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionJames Inglese论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionMarian H Harris论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionJohn M Asara论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionGregory Stephanopoulos论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionFrancesco G Salituro论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionShengfang Jin论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionLenny Dang论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionDouglas S Auld论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionHee-Won Park论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionLewis C Cantley论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionCraig J Thomas论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal TransductionMatthew G Vander Heiden论文数: 0 引用数: 0 h-index: 0机构: Beth Israel Deaconess Medical Center,Department of Medicine, Division of Signal Transduction
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- [25] Regulation and function of pyruvate kinase M2 in cancerCANCER LETTERS, 2013, 339 (02) : 153 - 158Yang, Weiwei论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Brain Tumor Ctr, Houston, TX 77030 USA Univ Texas MD Anderson Canc Ctr, Dept Neurooncol, Houston, TX 77030 USA Univ Texas MD Anderson Canc Ctr, Brain Tumor Ctr, Houston, TX 77030 USALu, Zhimin论文数: 0 引用数: 0 h-index: 0机构: Univ Texas MD Anderson Canc Ctr, Brain Tumor Ctr, Houston, TX 77030 USA Univ Texas MD Anderson Canc Ctr, Dept Neurooncol, Houston, TX 77030 USA Univ Texas MD Anderson Canc Ctr, Dept Mol & Cellular Oncol, Houston, TX 77030 USA Univ Texas Houston, Grad Sch Biomed Sci, Houston, TX 77030 USA Univ Texas MD Anderson Canc Ctr, Brain Tumor Ctr, Houston, TX 77030 USA
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