Otimization of the liquid-liquid extraction of nicotine in ternary solvent systems using surface response method

被引：0
|
作者：
Aznar, Martín [1 ]
Maduro, Raquel Moreira [1 ]
机构：
[1] Faculdade de Engenharia Química, Universidade Estadual de Campinas - UNICAMP, Caixa Posta 6066, CEP: 13081-970, Campinas, SP, Brazil
来源：
| 2008年 / University Federal de Uberlandia卷 / 17期
关键词：
Solutions;
D O I：
暂无
中图分类号：
O62 [有机化学]; TQ [化学工业];
学科分类号：
070303 ; 0817 ; 081704 ;
摘要：
This work aimed to optimize the agitation and rest times in recovery of nicotine from aqueous solutions by liquid-liquid extraction using response surface methodology seeking to maximize the percentage of nicotine in organic phase in liquidliquid equilibrium. The work based in experimental data of the liquid-liquid equilibrium of the ternary system nicotine + water + toluene at 303.15 K. With the use of the central composite design it was possible to estimate with a 95 % of probability for the Student t-test the optimum times of the agitation and rest times as 4 h and 20 h, respectively.
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