Studies on the relationship between vitamin D receptor gene polymorphism and osteoporosis in postmenopausal women

被引：0

作者：

Chen, Jun ^{[1
]}

Zhang, Li-Ping ^{[1
]}

Qiu, Jun-Feng ^{[1
]}

Peng, Hui ^{[1
]}

Deng, Zhong-Liang ^{[1
]}

Wang, Yu-Jun ^{[1
]}

Yan, Zhong-De ^{[1
]}

机构：

[1] Department of Endocrinology, Second Teaching Hospital, Chongqing Medical University, Chongqing 400010, China

来源：

Chinese Journal of Medical Genetics | 2003年 / 20卷 / 02期

关键词：

Genetic engineering - Patient monitoring - Vitamins;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Objective: To determine the relationship between vitamin D receptor (VDR) gene polymorphism and osteoporosis in postmenopausal women. Methods: The polymerase chain reaction-restriction fragment length polymorphism was used to detect VDR genotype in 40 patients with osteoporosis and 21 healthy postmenopausal women. Results: In the patients with osteoporosis, the bb, Bb, and BB genotype accounted for 82.5%, 17.5% and 0, respectively; in healthy groups, they were 85. 71%, 14.29% and 0, respectively (P>0.05). Conclusion: Significant association between VDR genotype and osteoporosis in Chinese women was observed in this study.

引用

页码：167 / 168

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