Screening of small molecule inhibitors against RhoA protein from Alisma using an online detection system

被引:0
|
作者
Yan, Chenjia [1 ]
Wang, Hong [1 ]
Chen, Shizhong [1 ]
机构
[1] Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, No. 38 Xueyuan Road, Haidian District, Beijing,100191, China
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Identification of small molecule inhibitors of the Chloracidobacterium thermophilum type IV pilus protein PilB by ensemble virtual screening
    McDonald-Ramos, Jay S.
    Hicklin, Ian K.
    Yang, Zhaomin
    Brown, Anne M.
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2024, 760
  • [42] Functional recombinant human Legumain protein expression in Pichia pastoris to enable screening for Legumain small molecule inhibitors
    Zhao, Tian
    Li, Zhipeng
    Guo, Zhouliang
    Wang, Ali
    Liu, Zhenxing
    Zhao, Qing
    Li, Yuyin
    McKenzie, Edward A.
    Diao, Aipo
    PROTEIN EXPRESSION AND PURIFICATION, 2018, 150 : 12 - 16
  • [43] High-Throughput Screening for Small-Molecule Inhibitors of LARG-Stimulated RhoA Nucleotide Binding via a Novel Fluorescence Polarization Assay
    Evelyn, Chris R.
    Ferng, Timothy
    Rojas, Rafael J.
    Larsen, Martha J.
    Sondek, John
    Neubig, Richard R.
    JOURNAL OF BIOMOLECULAR SCREENING, 2009, 14 (02) : 161 - 172
  • [44] Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach
    Duffy, Margaret R.
    Parker, Alan L.
    Kalkman, Eric R.
    White, Katie
    Kovalskyy, Dmytro
    Kelly, Sharon M.
    Baker, Andrew H.
    JOURNAL OF CONTROLLED RELEASE, 2013, 170 (01) : 132 - 140
  • [45] Discovery of Small Molecule Inhibitors and Activators of Death Receptor 5 Signaling using High Throughput Screening
    Young, Malaney
    Vunnam, Nagamani
    Lo, Chih Hung
    Sachs, Jonathan N.
    BIOPHYSICAL JOURNAL, 2021, 120 (03) : 205A - 205A
  • [46] Elucidating Protein-protein Interactions Through Computational Approaches and Designing Small Molecule Inhibitors Against them for Various Diseases
    Sarkar, Sharanya
    Gulati, Khushboo
    Kairamkonda, Manikyaprabhu
    Mishra, Amit
    Poluri, Krishna Mohan
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2018, 18 (20) : 1719 - 1736
  • [47] Discovery of Small Molecule Inhibitors of Protein-Protein Interactions Using Combined Ligand and Target Score Normalization
    Casey, Fergal P.
    Pihan, Emilie
    Shields, Denis C.
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2009, 49 (12) : 2708 - 2717
  • [48] Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel
    Zhang, Si Min
    Paulin, Cynthia B. J.
    Shu, Huazhang
    Yagu-Capilla, Miriam
    Michel, Maurice
    Marttila, Petra
    Ortis, Florian
    Bwanika, Henri Colyn
    Dirks, Christopher
    Venkatram, Rajagopal Papagudi
    Wiita, Elisee
    Jemth, Ann-Sofie
    Almlof, Ingrid
    Loseva, Olga
    Hormann, Femke M.
    Koolmeister, Tobias
    Linde, Erika
    Lee, Sun
    Llona-Minguez, Sabin
    Haraldsson, Martin
    Axelsson, Hanna
    Stromberg, Kia
    Homan, Evert J.
    Scobie, Martin
    Lundback, Thomas
    Helleday, Thomas
    Rudd, Sean G.
    ISCIENCE, 2024, 27 (02)
  • [49] Investigating PERK biological pathway using protein/peptide microarrays and SAR with small molecule inhibitors
    Otlik, Hubert
    Timofeevski, Sergei
    Quenzer, Terri
    Briere, David
    Fanjul, Andrea
    Alton, Gordon
    Ermolieff, Jacques
    MOLECULAR CANCER THERAPEUTICS, 2009, 8 (12)
  • [50] Label-Free Detection of G Protein-SNARE Interactions and Screening for Small Molecule Modulators
    Wells, Christopher A.
    Betke, Katherine M.
    Lindsley, Craig W.
    Hamm, Heidi E.
    ACS CHEMICAL NEUROSCIENCE, 2012, 3 (01): : 69 - 78