Effect of metal nanoparticles on biofilm formation of streptococcus mutans

被引:0
|
作者
Hashimoto M. [1 ]
Yanagiuchi H. [2 ]
Kitagawa H. [2 ]
Yamaguchi S. [2 ]
Honda Y. [1 ]
Imazato S. [2 ]
机构
[1] Institute of Dental Research, Osaka Dental University, 8-1, Kuzuha Hanazono-cho, Hirakata, Osaka
[2] Department of Biomaterials Science, Graduate School of Dentistry, Osaka University, Osaka
基金
日本学术振兴会;
关键词
Biofilm; Capping agent; Nanoparticle; Streptococcus mutans;
D O I
10.11344/nano.9.61
中图分类号
学科分类号
摘要
Metal nanoparticles (NPs) have the potential for use in infection control in the oral environment by killing bacteria or preventing plaque formation. However, little is known about their antibacterial properties against oral bacteria. The purpose of this study was to evaluate the antibacterial and biofilm inhibitory effects of gold (Au) and silver (Ag) NPs against S. mutans. Two NPs stabilized by metal-carbon σ-bonds between their core metal surfaces and the aromatic ring moieties were tested. This study evaluated the effect of NPs with the same surface chemistry but with two different core metal compositions (Au and Ag) on antibacterial activity. The antibacterial activity of both NPs was relatively weak. AgNPs exhibited a biofilm inhibitory effect against S. mutans; however, no inhibitory effect was found in AuNPs. © 2018 National Institute of Informatics. All rights reserved.
引用
收藏
页码:61 / 68
页数:7
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