Peptide-functionalized liposomes as therapeutic and diagnostic tools for cancer treatment

被引:0
|
作者
Sonju, Jafrin Jobayer [1 ]
Dahal, Achyut [1 ]
Singh, Sitanshu S. [1 ]
Jois, Seetharama D. [1 ]
机构
[1] School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe,LA,71201, United States
关键词
Anti-cancer therapies - Anticancer effects - Cancer drug deliveries - Diagnostic tools - Drug formulations - Liposomal formulation - Surface Functionalization - Therapeutic efficacy;
D O I
暂无
中图分类号
学科分类号
摘要
Clinically efficacious medication in anticancer therapy has been successfully designed with liposome-based nanomedicine. The liposomal formulation in cancer drug delivery can be facilitated with a functionalized peptide that mediates the specific drug delivery opportunities with increased drug penetrability, specific accumulation in the targeted site, and enhanced therapeutic efficacy. This review aims to focus on recent advances in peptide-functionalized liposomal formulation techniques in cancer diagnosis and treatment regarding recently published literature. It also will highlight different aspects of novel liposomal formulation techniques that incorporate surface functionalization with peptides for better anticancer effect and current challenges in peptide-functionalized liposomal drug formulation. © 2020 Elsevier B.V.
引用
收藏
页码:624 / 644
相关论文
共 50 条
  • [21] A Peptide-functionalized delivery system to target osteoclasts
    Zhang, Ge
    Dang, Lei
    Guo, Baosheng
    Li, Defang
    Liu, Jin
    Liang, Chao
    He, Xiaojuan
    Wu, Heng
    Yang, Zhijun
    Liang, Zicai
    Lu, Aiping
    JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 : S248 - S248
  • [22] Enhancing transdermal delivery of chrysomycin A for the treatment of cutaneous melanoma and MRSA infections using Skin-Penetrating Peptide-Functionalized deformable liposomes
    Cai, Yue
    Zhang, Xinrui
    Hu, Wentao
    Song, Fuhang
    Wang, Hong
    Zhang, Huawei
    Sun, Xuanrong
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 670
  • [23] Peptide-functionalized nanoparticles for targeted delivery of therapeutics
    Kokkoli, Efrosini
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [24] Peptide-functionalized surfaces for rationally designed biotechnology
    Fiesl, Whitney
    Webb, Lauren
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255
  • [25] Molecular modeling to predict peptide accessibility for peptide-functionalized hydrogels
    Li, Xianfeng
    Jia, Jia
    Mei, Ying
    Latour, Robert A.
    BIOINTERPHASES, 2017, 12 (03)
  • [26] Zwitterionic peptide-functionalized highly dispersed carbon nanotubes for efficient wastewater treatment
    Huang, Jie
    Sui, Xiaojie
    Qi, Haishan
    Lan, Xiang
    Liu, Simin
    Zhang, Lei
    JOURNAL OF MATERIALS CHEMISTRY B, 2022, 10 (14) : 2661 - 2669
  • [27] HER2 status of CTCs by peptide-functionalized nanoparticles as the diagnostic biomarker of breast cancer and predicting the efficacy of anti-HER2 treatment
    Wang, Mengting
    Liu, Yaxin
    Shao, Bin
    Liu, Xiaoran
    Hu, Zhiyuan
    Wang, Chen
    Li, Huiping
    Zhu, Ling
    Li, Ping
    Yang, Yanlian
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2022, 10
  • [28] Synthesis and characterization of peptide-functionalized polymeric nanoparticles
    Taylor, S
    Qu, LW
    Kitaygorodskiy, A
    Teske, J
    Latour, RA
    Sun, YP
    BIOMACROMOLECULES, 2004, 5 (01) : 245 - 248
  • [29] Peptide-Functionalized Nanogels for Targeted siRNA Delivery
    Blackburn, William H.
    Dickerson, Erin B.
    Smith, Michael H.
    McDonald, John F.
    Lyon, L. Andrew
    BIOCONJUGATE CHEMISTRY, 2009, 20 (05) : 960 - 968
  • [30] Dual-ligand peptide-functionalized liposomes targeting α5β1 and α6β4 integrins enhance gene delivery and selectivity to cancer cells
    Levine, Rachel
    Kokkoli, Efrosini
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253