The response surface methodology is used to evaluate the effect of temperature, pressure, number of vacuum pulse and syrup/fruit ratio, over color parameters such as luminosity, chromatic parameters, and color difference (L∗, a∗, b∗ y dE∗), humidity and solid soluble contain, texture (hardness), acidity and water activity, in osmotic dehydration of avocado (Persea americana) var. Hass. A solution of maltodextrin (50%), NaCl (10%), citric acid (1.5%) and ascorbic acid (1.5%), during 4 h was employed. The results show that it is possible to reduce color damage and to improve others characteristic of avocado with osmotic dehydration to 7.5 °C and 850 mBar. Under these conditions the kinetic behavior in osmotic dehydration of avocado was determined, using two empirical equations and a phenomenological model.