Application of volatile organic compound detection method for human breath in non-invasive diagnosis of lung cancer

Lung cancer is one of the most common and the most lethal malignant tumors. Since lung cancer is almost asymptomatic in its early stage, most of them are advanced when diagnosed. Early detection can improve the survival rate of lung cancer, therefore, early diagnosis of lung cancer is essential. Breath analysis method has the advantages of rapid, non-invasive, convenient sampling and human friendly, leading to its great potential for early screening of lung cancer. In this paper, the methods of sampling and enrichment of volatile organic compounds (VOCs) in human breath and the applications of different detection techniques in lung cancer were reviewed, and their limitations and future development trends were discussed. © 2024, Youke Publishing Co.,Ltd. All rights reserved.