A toehold mediated feedback rolling circle amplification with exponential signal amplification enables label-free nucleic acid sensing with high sensitivity and specificity

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作者
Huang, Ting [1 ]
Zhu, Daozhong [1 ,2 ]
Li, Tong [1 ]
Sun, Mengxu [1 ]
Chen, Guixun [1 ]
Zhang, Yanxin [1 ]
Chen, Jin-Xiang [1 ]
Zou, Xiaoyong [4 ]
Dai, Zong [3 ]
Chen, Jun [1 ]
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[1] NMPA Key Laboratory for Research and Evaluation of Drug Metabolism, Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou,510515, China
[2] Guangzhou Customs Technology Center, People's Republic of China, Guangzhou,510623, China
[3] Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Shenzhen,518107, China
[4] School of Chemistry, Sun Yat-Sen University, Guangzhou,510275, China
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