Development and validation of a method for detecting contaminants in nalmefene hydrochloride injections

被引：0
|
作者：
Duan M. [1 ]
Li X. [1 ]
Liu B. [2 ]
Pan X. [3 ]
Sun R. [3 ]
Li Y. [1 ]
机构：
[1] Changchun University of Chinese Medicine, Changchun, 1300107, Jilin
[2] Changchun Obstetrics-Gynecology Hospital, Changchun, 130022, Jilin
[3] Changchun Qinghe Street Office, Changchun, 130022, Jilin
来源：
International Journal of Simulation: Systems, Science and Technology | 2016年 / 17卷 / 44期
关键词：
Detecting contaminants; Nalmefene hydrochloride injection; Validation;
D O I：
10.5013/IJSSST.a.17.44.13
中图分类号：
学科分类号：
摘要：
Nalmefene hydrochloride injection is a first-line drug in emergency management to relieve respiratory depression, but its poor stability limits its clinical application. We aimed to develop and thoroughly validate a detection method for impurities in nalmefene hydrochloride injection and provide a foundation for studies of product stability. © 2016, UK Simulation Society. All rights reserved.
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页码：13.1 / 13.4
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