Isopentenyl diphosphate isomerase. Mechanism-based inhibition by diene analogues of isopentenyl diphosphate and dimethylallyl diphosphate

被引：0
|
作者：
Wu, Zheng [1 ]
Wouters, Johan [2 ,3 ]
Poulter, C. Dale [1 ]
机构：
[1] Department of Chemistry, University of Utah, Salt Lake City, UT 84112, United States
[2] Laboratoire de Chimie Biologique Structurale, 61 Rue de Bruxelles, Namur, Belgium
[3] Institut de Recherches Wiame, Campus Ceria, Bruxelles, Belgium
来源：
Journal of the American Chemical Society | 2005年 / 127卷 / 49期
关键词：
Number:; R01GM025521; Acronym:; NIGMS; Sponsor: National Institute of General Medical Sciences;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：17433 / 17438
相关论文
共 50 条
  • [31] Stereochemical Studies of the Type II Isopentenyl Diphosphate-Dimethylallyl Diphosphate Isomerase Implicate the FMN Coenzyme in Substrate Protonation
    Calveras, Jordi
    Thibodeaux, Christopher J.
    Mansoorabadi, Steven O.
    Liu, Hung-wen
    CHEMBIOCHEM, 2012, 13 (01) : 42 - 46
  • [32] Synthesis and biological activity of isopentenyl diphosphate analogues
    Scholte, AA
    Eubanks, LM
    Poulter, CD
    Vederas, JC
    BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (04) : 763 - 770
  • [33] QM/MM studies of the type II isopentenyl diphosphate-dimethylallyl diphosphate isomerase demonstrate a novel role for the flavin coenzyme
    Hou, Qianqian
    Wang, Kang
    Xu, Feng
    Zhang, Wenshen
    Ji, Kejian
    Liu, Yongjun
    RSC ADVANCES, 2017, 7 (36): : 22286 - 22293
  • [34] The type II isopentenyl Diphosphate:Dimethylallyl diphosphate isomerase (IDI-2): A model for acid/base chemistry in flavoenzyme catalysis
    Thibodeaux, Christopher J.
    Liu, Hung-Wen
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2017, 632 : 47 - 58
  • [35] Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli
    Rodríguez-Concepción, M
    Campos, N
    Lois, LM
    Maldonado, C
    Hoeffler, JF
    Grosdemange-Billiard, C
    Rohmer, M
    Boronat, A
    FEBS LETTERS, 2000, 473 (03) : 328 - 332
  • [36] ISOPENTENYL-DIPHOSPHATE ISOMERASE - IRREVERSIBLE INHIBITION BY 3-METHYL-3,4-EPOXYBUTYL DIPHOSPHATE
    LU, XJ
    CHRISTENSEN, DJ
    POULTER, CD
    BIOCHEMISTRY, 1992, 31 (41) : 9955 - 9960
  • [37] HYDROGEN-EXCHANGE DURING THE ENZYME-CATALYZED ISOMERIZATION OF ISOPENTENYL DIPHOSPHATE AND DIMETHYLALLYL DIPHOSPHATE
    STREET, IP
    CHRISTENSEN, DJ
    POULTER, CD
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (23) : 8577 - 8578
  • [38] Proton exchange in type II isopentenyl diphosphate isomerase
    Barkley, SJ
    Desai, SB
    Poulter, CD
    ORGANIC LETTERS, 2004, 6 (26) : 5019 - 5021
  • [39] Type-2 Isopentenyl Diphosphate Isomerase: Evidence for a Stepwise Mechanism
    Heaps, Nicole A.
    Poulter, C. Dale
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2011, 133 (47) : 19017 - 19019
  • [40] Cloning, expression and characterization of lepidopteran isopentenyl diphosphate isomerase
    Sen, Stephanie E.
    Tomasello, Ashley
    Grasso, Michael
    Denton, Ryan
    Macor, Joseph
    Beliveau, Catherine
    Cusson, Michel
    Crowell, Dring N.
    INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2012, 42 (10) : 739 - 750
12345