Synthesis of chlorooxazoles related to natural products

被引：0

作者：

Radspieler, A. ^{[1
]}

Liebscher, J. ^{[1
]}

机构：

[1] Institut für Chemie, Humboldt-Universität Berlin, Hessische Straße 1-2, 10115 Berlin, Germany

来源：

Synthesis | 2001年 / 05期

关键词：

Aldehydes - Cyanides - Derivatives - Substitution reactions - Synthesis (chemical);

D O I：

10.1055/s-2001-12771

中图分类号：

学科分类号：

摘要：

2-Chloro-3-(4-chlorooxazole-5-yl)-indoles and 4-chloro-5-phenyl-oxazoles 3 were synthesised from acyl cyanides 1, aldehydes 2 and hydrogen chloride. By further derivatisation of the substituent at position 2 of the 4-chlorooxazole ring, useful potential building blocks 31, 3n and 3o for a total synthesis of diazonamide A, were obtained.

引用

页码：745 / 750

共 50 条

[41] ORGN 372-Organic synthesis and methodology for artemisinin and related natural products
Dudley, Gregory B.
Lam, Hubert
Poon, Kevin W. C.
Engel, Douglas A.
Singletary, Jeananne A.
Lopez, Susana
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 232
[42] Synthesis of Antimicrobial Natural Products Targeting FtsZ: (+)-Totarol and Related Totarane Diterpenes
Kim, Michelle B.
Shaw, Jared T.
ORGANIC LETTERS, 2010, 12 (15) : 3324 - 3327
[43] Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues
Ishikawa, Hayato
Colby, David A.
Seto, Shigeki
Va, Porino
Tam, Annie
Kakei, Hiroyuki
Rayl, Thomas J.
Hwang, Inkyu
Boger, Dale L.
Journal of the American Chemical Society, 2009, 131 (13): : 4904 - 4916
[44] Total Synthesis of 4'-O-Methylgrynullarin and Related Isoflavone Natural Products
Okada, Takuya
Nguyen Ngoc Thanh Luan
Arata, Ruka
Awale, Suresh
Toyooka, Naoki
CHEMISTRYSELECT, 2022, 7 (15):
[45] Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues
Ishikawa, Hayato
Colby, David A.
Seto, Shigeki
Va, Porino
Tam, Annie
Kakei, Hiroyuki
Rayl, Thomas J.
Hwang, Inkyu
Boger, Dale L.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (13) : 4904 - 4916
[46] Synthesis of a spirocyclic amine related to the marine natural products halichlorine and pinnaic acid
Clive, DLJ
Wang, H
Yu, ML
TETRAHEDRON LETTERS, 2005, 46 (16) : 2853 - 2855
[47] Applications of visible light photoredox catalysis to the synthesis of natural products and related compounds
Nicholls, Thomas P.
Leonori, Daniele
Bissember, Alex C.
NATURAL PRODUCT REPORTS, 2016, 33 (11) : 1248 - 1254
[48] Targeted natural products synthesis
Leighton, JL
CHEMICAL & ENGINEERING NEWS, 2001, 79 (13) : 234 - 234
[49] Synthesis of marine natural products
Chen, Chuo
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
[50] SYNTHESIS AND NATURAL-PRODUCTS
DANISHEFSKY, SJ
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1986, 191 : 110 - ORGN

← 1 2 3 4 5 →