The properties of bacterial adaptation to mono- and bis-quaternary ammonium compounds

被引：0
|
作者：
Tabata, Atsushi [1 ]
Maeda, Takuya [1 ]
Nagamune, Hideaki [1 ]
Kourai, Hiroki [1 ]
机构：
[1] Dept. of Biological Sci./Technology, Faculty of Engineering, University of Tokushima, Minamijosanjima-cho, Tokushima 770-8506, Japan
来源：
Biocontrol Science | 2003年 / 8卷 / 01期
关键词：
Bacteria; -; Hydrophilicity; Hydrophobicity;
D O I：
10.4265/bio.8.37
中图分类号：
学科分类号：
摘要：
The adaptation of bacteria to mono- and bis-type quaternary ammonium compounds (QACs) was carried out and studied. The minimum inhibitory concentration (MIC) of bis-QACs against the bacteria in contact with bis-QACs was nearly the same as that against the control. However, the MIC of mono-QAC against the strains adapted to mono-QAC was higher than that against the control. Moreover, bis-QACs were effective against even the strains adapted to mono-QAC. As the cell surface of the strains adapted to mono-QAC changed to hydrophilic, the difference in the bacterial adaptation was thought to arise from a potent property of bis-QACs whose antimicrobial characteristics are independent of the change in the cell surface hydrophobicity.
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页码：37 / 42
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