Polymer supports in synthesis

被引：0

作者：

Pittman Jr., Charles U. ^{[1
]}

机构：

[1] Univ./Indust. Chem. Research Center, Department of Chemistry, Mississippi State University, Mississippi State, MS 39762, United States

来源：

Polymer News | 2004年 / 29卷 / 12期

关键词：

Amino acids - Chromatography - Esterification - Hydrophilicity - Molecular structure - Negative ions - Organic compounds - Polymers - Polypeptides - Proteins - Substitution reactions - Synthesis (chemical);

D O I：

10.1080/00323910490981669

中图分类号：

学科分类号：

摘要：

The developments of a novel sucrose-based polymer support (SUBPOL) for both solid-phase peptide synthesis and affinity chromatography are discussed. A solid-phase oligodeoxynucleotide two-step synthetic cycle, using peroxy anion protection, was also studied. The purpose of making the SUBPOL resin was to create a hydrophilic support resin, to which is attached a short synthetic peptide. The SUBPOL serves as as affinity ligand for purification of macromolecules proteins from blood plasma.

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页码：376 / 378

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