Chiral 1,3-octanediol synthetic studies using enzymatic methods as key steps

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作者
Nozaki, M. [1 ]
Ikeuchi, M. [1 ]
Suzuki, N. [1 ]
机构
[1] Central Research Laboratory, Takasago International Corporation, 1-4-11, Nishi-Yawata, Hiratuka, 254-0073, Japan
来源
ACS Symposium Series | 2001年 / 794卷
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摘要
Synthesis of both enantiomers of 1,3-octanediol was accomplished via chiral 1-octen-3-ol. Enzymatic optical resolution was adopted as the key step for obtaining chiral 1-octen-3-ol. Both enantiomers of 1,3-octanediol were transformed into their glucosides enzymatically. The acetals of the diol were also synthesized. Enzymatic reaction played a major role in the synthesis of chiral 1,3-octanediol and its derivatives. Sensory evaluation was performed on all of the samples.
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页码:208 / 217
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