Effects of Polysaccharides fromCrataegus songoricaK. Koch. Fruits on D-Galactose-Induced Aging Mice

This purpose of this study was to explore the effect of polysaccharides extracted from the residue left after the extraction of anthocyanins from Crataegus songorica K. Koch. fruits on D-galactose-induced aging mice. The polysaccharides were prepared by water extraction and alcohol precipitation and were orally administered to D-galactoseinduced aging mice at three different doses (200, 400 and 800 mg/kg). Glutathione peroxidase (GSH-Px) activity,total antioxidative capability (T-AOC) and malondialdehyde (MDA) content in brain, liver and serum were measured.Histological extraction of liver and brain tissues was carried out as well. The results showed that high-dose polysaccharide could significantly improve the activity of GSH-Px in liver and serum (P © 2018, China Food Publishing Company. All right reserved.