PD-1 and LAG-3 dual blockade: emerging mechanisms and potential therapeutic prospects in cancer

被引:0
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作者
Xiangyu Qiu
Zhaoan Yu
Xiaoqing Lu
Xin Jin
Jinrong Zhu
Rongxin Zhang
机构
[1] GuangdongProvincialKeyLaboratoryofAdvancedDrugDelivery,GuangdongProvincialEngineeringCenterofTopicalPreciseDrugDeliverySystem,SchoolofLifeSciencesandBiopharmaceutics,GuangdongPharmaceuticalUniversity
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中图分类号
R730.5 [肿瘤治疗学];
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摘要
<正>The emergence of tumor immunotherapy represents a pivotal milestone in cancer treatment, heralding new hope for cancer patients globally. Immune checkpoint inhibitors have been instrumental in this advance, playing a crucial role in modulating the immune system response to neoplasms. Specifically, the therapies targeting the programmed death 1/programmed cell death ligand 1(PD-1/PD-L1) immune checkpoint pathways have shown significant efficacy in treating various cancers1.
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页码:970 / 976
页数:7
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