Remarkable and Unexpected Mechanism for (S)-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase

被引：0

作者：

Zhu, Wei ^{[1
]}

Doubleday, Peter F. ^{[2
]}

Butrin, Arseniy ^{[3
]}

Weerawarna, Pathum M. ^{[1
]}

Melani, Rafael D. ^{[2
]}

Catlin, Daniel S. ^{[3
]}

Dwight, Timothy A. ^{[1
]}

Liu, Dali ^{[3
]}

Kelleher, Neil L. ^{[1
,2
]}

Silverman, Richard B. ^{[1
,2
,4
]}

机构：

[1] Department of Chemistry, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Center for Developmental Therapeutics, Northwestern University, Evanston,IL,60208, United States

[2] Department of Molecular Biosciences, Northwestern University, Evanston,IL,60208, United States

[3] Department of Chemistry and Biochemistry, Loyola University Chicago, Chicago,IL,60660, United States

[4] Department of Pharmacology, Northwestern University, Chicago,IL,60611, United States

来源：

Journal of the American Chemical Society | 2021年 / 143卷 / 21期

关键词：

Enzymes;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：8193 / 8207

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