The proliferation of mobile devices around the world, combined with falling costs of hardware and Internet connectivity, have resulted in an increasing number of organizations that work to introduce educational technology interventions into low-income schools in the Global South. However, to date, most prior HCI research examining such interventions has focused on interventions that target students. In this paper, we expand prior literature by examining an intervention, called Meghshala, that targets teachers in low-income schools as its primary users. Through interviews and observations with 39 participants from 12 government schools in India, we show how the introduction of a teacher-focused technology intervention causes teachers to reconfigure their work practices, including lesson preparation, in-classroom teaching practices, bureaucratic work processes, and post-teaching feedback mechanisms. We use the concept of material agency to analyze our findings with respect to teacher agency and reconfiguration, and use theories of teacher knowledge to highlight the kinds of knowledge production that teachers in our research context tend to focus on (e.g., content knowledge). Finally, we offer design opportunities for future teacher-focused technology interventions. © 2019 Copyright held by the owner/author(s). Publication rights licensed to ACM.