Determination of l-tryptophan in whole blood samples using a new electrochemical sensor

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作者
Ilie, Ruxandra Maria [1 ,2 ]
Stefan-Van Staden, Raluca-Ioana [1 ,2 ]
机构
[1] Department of Analytical Chemistry and Environmental Engineering, University POLITEHNICA of Bucharest, Romania
[2] Laboratory of Electrochemistry and PATLAB Bucharest, National Institute of Research for Electrochemistry and Condensed Matter, Department of Analytical Chemistry and Environmental Engineering, University POLITEHNICA of Bucharest, Romania
关键词
Voltammetry - Amino acids - Blood;
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摘要
L-tryptophan is an amino acid used as biomarker for the diagnosis of gastric cancer. A new electrochemical sensor based on graphite paste modified with 2,6-bis((E)-2-(furan-2-yl)vinyl)-4-(4,6,8-trimethylazulen-1-yl)pyridine was proposed for its determination in real whole blood samples. Differential pulse voltammetry was used for all determinations. The limit of detection, sensitivity, and selectivity made possible its determination in whole blood samples with recoveries higher than 90.00% with RSD less than 1.00%. © 2019, Politechnica University of Bucharest. All rights reserved.
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页码:42 / 46
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