Selective Protein of Interest Degradation through the Split-and-Mix Liposome Proteolysis Targeting Chimera Approach

被引:0
|
作者
Song, Chunli [1 ]
Jiao, Zijun [2 ,4 ]
Hou, Zhanfeng [1 ]
Wang, Rui [2 ]
Lian, Chenshan [1 ]
Xing, Yun [1 ]
Luo, Qinhong [1 ,2 ,3 ]
An, Yuhao [2 ]
Yang, Fenfang [1 ]
Wang, Yuechen [1 ]
Sha, Xinrui [2 ]
Ruan, Zhijun [2 ]
Ye, Yuxin [2 ]
Liu, Zhihong [2 ]
Li, Zigang [1 ,2 ,4 ]
Yin, Feng [1 ,2 ]
机构
[1] State Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen,518055, China
[2] Pingshan Translational Medicine Center, Shenzhen Bay Laboratory, Shenzhen,518118, China
[3] Department of Pharmacy, Department of Gastrointestinal Surgery, Shenzhen Second People’s Hospital (Shenzhen Institute of Translational Medicine), Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology
[4] Frontiers Medical Center, Tianfu Jincheng Laboratory, Sichuan, Chengdu,610212, China
来源
关键词
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:21860 / 21870
相关论文
共 25 条
  • [21] Bet Protein Degradation With The Proteolysis-targeting Chimera, Dbet1, Ameliorates Brain Damage And Neurological Deficits After Transient Cerebral Ischemia
    Liu Lei
    Yang Changjun
    Lavayen, Bianca P.
    Larochelle, Jonathan
    Candelario-jalil, Eduardo
    STROKE, 2022, 53
  • [22] Selective degradation of BET proteins with dBET1, a proteolysis-targeting chimera, potently reduces pro-inflammatory responses in lipopolysaccharide-activated microglia
    DeMars, Kelly M.
    Yang, Changjun
    Castro-Rivera, Carolina I.
    Candelario-Jalil, Eduardo
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 497 (01) : 410 - 415
  • [23] Enhanced Tumor Targeting and Penetration of Proteolysis-Targeting Chimeras through iRGD Peptide Conjugation: A Strategy for Precise Protein Degradation in Breast Cancer
    He, Shipeng
    Fang, Yuxin
    Wu, Minghao
    Zhang, Peifeng
    Gao, Fei
    Hu, Honggang
    Sheng, Chunquan
    Dong, Guoqiang
    JOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (24) : 16828 - 16842
  • [24] Selective targeting of non-centrosomal AURKA functions through use of a targeted protein degradation tool
    Wang, Richard
    Ascanelli, Camilla
    Abdelbaki, Ahmed
    Fung, Alex
    Rasmusson, Tim
    Michaelides, Iacovos
    Roberts, Karen
    Lindon, Catherine
    COMMUNICATIONS BIOLOGY, 2021, 4 (01)
  • [25] Selective targeting of non-centrosomal AURKA functions through use of a targeted protein degradation tool
    Richard Wang
    Camilla Ascanelli
    Ahmed Abdelbaki
    Alex Fung
    Tim Rasmusson
    Iacovos Michaelides
    Karen Roberts
    Catherine Lindon
    Communications Biology, 4