Preparation and Antibacterial Function of an Cu-bearing Chitosan Coating on Silicone Rubber Surface

被引：0

作者：

Wang L. ^{[1
]}

Guan H. ^{[1
]}

Chen S. ^{[2
]}

Zhang B. ^{[2
]}

Yang K. ^{[2
]}

机构：

[1] Department of Chemistry, Liaoning University, Shenyang

[2] Institute of Metal Research, Chinese Academy of Sciences, Shenyang

来源：

Guan, Hongyu (guanhongyu@lnu.edu.cn); Chen, Shanshan (sschen@imr.ac.cn) | 1600年 / Chinese Journal of Materials Research卷 / 34期

关键词：

Bonding ability; Functional coating; Silicone rubber catheter; Stepwise chemical grafting; Surface and interface of material;

D O I：

10.11901/1005.3093.2020.047

中图分类号：

学科分类号：

摘要：

In order to solve the infection caused by the indwelling catheter, an anti-infective Cu-bearing chitosan coating was prepared on the silicone rubber surface. But it is difficult to prepare a coating on the surface of silicone rubber due to its biological inertness. Therefore, chemical grafting was used to activate the silicone rubber by the dopamine pretreatment, which provides abundant functional groups on the activated silicone rubber surface. The surface morphology and surface properties of the silicone rubber after surface activation pretreatment were characterized by the active functional groups. Onto which, subsequently, the Cu-bearing chitosan coating could be chemically grafted, and then the surface morphology was compared for the coatings before and after immersion test. The effectiveness of pretreatment process was assessed by the bonding force between the functionalized coating and the silicone rubber. It follows that the abundant functional groups offered by the pretreatment on the activated silicone rubber surface may be beneficial for enhancing the adhesive strength of the functionalized coating to the silicon rubber. Thereby, the Cu-bearing chitosan coating makes the silicone rubber catheter have good antibacterial function. © 2020, Editorial Office of Chinese Journal of Materials Research. All right reserved.

引用

页码：575 / 583

页数：8