Facile synthesis of copper sulfide loaded mesoporous organosilica nanospheres with a triple-shelled hollow structure

被引:0
|
作者
Shi, Xuzhi [2 ]
Yu, Yifeng [1 ]
Yu, Ruifa [2 ]
Wang, Ning [2 ]
Lu, Wei [2 ]
Han, Xiaolin [2 ]
Sun, Tangyao [2 ]
Li, Pengcheng [1 ]
Su, Xiaodan [2 ]
Teng, Zhaogang [2 ]
Liu, Ying [3 ]
机构
[1] Wuhan Univ, Zhongnan Hosp, Dept Orthoped Trauma & Microsurg, Wuhan 430071, Peoples R China
[2] Nanjing Univ Posts & Telecommun, Key Lab Organ Elect & Informat Displays, Jiangsu Natl Synerget Innovat Ctr Adv Mat, Jiangsu Key Lab Biosensors,Inst Adv Mat, 9 Wenyuan Rd, Nanjing 210023, Peoples R China
[3] Wenzhou Univ Technol, Sch Intelligent Mfg & Elect Engn, Wenzhou 325025, Peoples R China
关键词
Mesoporous organosilica; Composite nanospheres; Hollow structure; Triple-shell; Photothermal; NANOPARTICLES;
D O I
10.1007/s10934-024-01668-8
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Herein, copper sulfide loaded mesoporous organosilica nanospheres with a triple-shelled hollow structure (CuS/tHMONs) are successfully synthesized. The resulting CuS/tHMONs nanospheres exhibit a uniform diameter of 340 nm, mesoporous channels with a diameter of 3.8 nm, large pore volume, and triply separated cavities. High-angle annular dark-field scanning electron microscopy (HAADF-STEM) images confirm the presence of a high content of CuS nanoparticles within the CuS/tHMONs composite nanospheres. Moreover, the CuS/tHMONs nanospheres demonstrate high photothermal conversion efficiency and excellent photothermal stability. In vitro experiments reveal excellent biocompatibility of the CuS/tHMON nanospheres, and cytotoxic assays demonstrate their effectiveness in killing cancer cells through photothermal therapy.
引用
收藏
页码:67 / 74
页数:8
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