Reusable microfluidic chip combining auto-electrode alignment with lateral microfluidic accesses for biomedical applications

While microfluidics offer a wide array of possibilities for cellular analysis, several issues still plague its automation as a Lab-On-Chip (LoC) device when electrodes need to be integrated and packaged with microfluidic accesses. In this work, a fully reusable and open-source setup microfluidic chip is presented allowing the casting and use of lateral access for microfluidic setup, to mitigate the effects of sedimentation on input as well as a fabrication setup for precise alignment of an easily dismounted LoC setup. Electric connections are combined with the closure of the channel taking advantage of an innovative packaging based on 3D printed and dedicated PCB having electrical tips.