DEVELOPMENT OF A HIGH THROUGHPUT SCREEN FOR CYTOCHROME P450-LIGAND BINDING ASSAYS

被引：0
|
作者：
Frydendall, Ellie [1 ]
机构：
[1] Univ Michigan, Ann Arbor, MI USA
来源：
DRUG METABOLISM AND PHARMACOKINETICS | 2024年 / 55卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A1
引用
收藏
页数：1
相关论文
共 50 条
  • [21] A virtual high throughput screen for high affinity cytochrome P450cam substrates. Implications for in silico prediction of drug metabolism
    György M. Keserű
    Journal of Computer-Aided Molecular Design, 2001, 15 : 649 - 657
  • [22] Kinetics and thermodynamics of ligand binding by cytochrome P450 3A4
    Isin, EM
    Guengerich, FP
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (14) : 9127 - 9136
  • [23] LIGAND INTERACTIONS WITH CYTOCHROME P-450 .I. BINDING OF PRIMARY AMINES
    JEFCOATE, CR
    GAYLOR, JL
    CALABRES.RL
    BIOCHEMISTRY, 1969, 8 (08) : 3455 - &
  • [24] Peripheral Ligand Binding and Allostery in Cytochrome P450 3A4
    Davydov, Dmitri R.
    Rumfeldt, Jessica A. O.
    Sineva, Elena V.
    Davydova, Nadezhda Y.
    Halpert, James R.
    FASEB JOURNAL, 2012, 26
  • [25] CW EPR parameters reveal cytochrome P450 ligand binding modes
    Lockart, Molly M.
    Rodriguez, Carlo A.
    Atkins, William M.
    Bowman, Michael K.
    JOURNAL OF INORGANIC BIOCHEMISTRY, 2018, 183 : 157 - 164
  • [26] Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases
    Podgorski, Matthew N.
    Harbort, Joshua S.
    Coleman, Tom
    Stok, Jeanette E.
    Yorke, Jake A.
    Wong, Luet-Lok
    Bruning, John B.
    Bernhardt, Paul, V
    De Voss, James J.
    Harmer, Jeffrey R.
    Bell, Stephen G.
    BIOCHEMISTRY, 2020, 59 (09) : 1038 - 1050
  • [27] Development of the "Inje cocktail'' for high-throughput evaluation of five human cytochrome p450 Isoforms in vivo
    Ryu, J. Y.
    Song, I. S.
    Sunwoo, Y. E.
    Shon, J. H.
    Liu, K. H.
    Cha, I. J.
    Shin, J. G.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2007, 82 (05) : 531 - 540
  • [28] Validated assays for human cytochrome P450 activities
    Walsky, RL
    Obach, RS
    DRUG METABOLISM AND DISPOSITION, 2004, 32 (06) : 647 - 660
  • [29] Miniaturization and automation of cytochrome P450 inhibition assays
    Marks, Bryan D.
    Larson, Brad
    DRUG METABOLISM REVIEWS, 2006, 38 : 61 - 62
  • [30] Ligand binding and catalytic properties of cytochrome P450s from Mycobacterium tuberculosis
    Vasilevskaya, A.
    Yantsevich, A.
    Grabovec, I.
    Usanov, S.
    Gilep, A.
    FEBS JOURNAL, 2013, 280 : 148 - 148
12345