Taking hydroxychloroquine to heart

被引:0
|
作者
Heymann, Warren R. [1 ]
机构
[1] Rowan Univ, Div Dermatol, Cooper Med Sch, Camden, NJ 08028 USA
关键词
antimalarials; cardiotoxicity; chloroquine; hydroxychloroquine;
D O I
10.1016/j.jaad.2024.07.1477
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
hydroxychloroquine (HCQ) was considered (and subsequently refuted) as a potential therapy against the SARS-CoV-2 virus. Reports of cardiotoxicity triggered controversy about appropriate cardiac monitoring in patients who were The antimalarial HCQ is a workhorse in medical including lupus erythematosus, dermatomyositis, and rheumatoid arthritis. Cardiotoxic effects associated with prolonged administration and high dosages of HCQ include bradycardia, tachycardia, block, and cardiomyopathy. Risk factors associated with cardiotoxicity include age [60 years, female nephritis, underlying cardiac disease, the presence of systemic inflammation, and COX inhibition.1,2 Before COVID-19, cardiac monitoring by electrocardiogram
引用
收藏
页码:676 / 677
页数:2
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