Gemigliptin Attenuates TGF-β-Induced Renal Fibrosis by Inhibiting the TGF-β/Smad3 Signaling Pathway through the Upregulation of FGF21 Expression

被引：0
|
作者：
Jung, Gwonsoo
机构：
来源：
DIABETES | 2024年 / 73卷
基金：
新加坡国家研究基金会;
关键词：
D O I：
10.2337/db24-392-P
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
392-P
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Scoparone attenuates hepatic stellate cell activation through inhibiting TGF-β/Smad signaling pathway
    Liu, Xing
    Zhao, Xiuxia
    BIOMEDICINE & PHARMACOTHERAPY, 2017, 93 : 57 - 61
  • [22] Hydrogen sulfide ameliorates rat myocardial fibrosis induced by hyperhomocysteinemia through TGF-β1/SMAD3 signaling pathway
    Yi, Jiali
    Liu, Shengquan
    Zheng, Xia
    Li, Yaling
    Nie, Liangui
    Wu, Qian
    Chen, Jian
    Zhang, Jingjing
    Chu, Chun
    Yang, Jun
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2019, 125 : 9 - 10
  • [23] Islet transplantation attenuates cardiac fibrosis in diabetic rats through inhibition of TGF-β1/Smad3 pathway
    Wang, Hong-Wei
    Chen, Yi-He
    Chen, Yan-Yan
    Huang, Wei
    Zhu, Xian-Dong
    Ni, Fu-Biao
    Wu, Guo-Di
    Xu, Zi-Qiang
    Huang, Zhou-Qing
    Chen, Bi-Cheng
    Xiao, Fang-Yi
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2018, 10 (08): : 2445 - 2456
  • [24] Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts
    Bing Tang
    Bin Zhu
    Yueying Liang
    Liangkuan Bi
    Zhicheng Hu
    Bin Chen
    Kai Zhang
    Jiayuan Zhu
    Archives of Dermatological Research, 2011, 303 : 563 - 572
  • [25] Asiaticoside suppresses collagen expression and TGF-β/Smad signaling through inducing Smad7 and inhibiting TGF-βRI and TGF-βRII in keloid fibroblasts
    Tang, Bing
    Zhu, Bin
    Liang, Yueying
    Bi, Liangkuan
    Hu, Zhicheng
    Chen, Bin
    Zhang, Kai
    Zhu, Jiayuan
    ARCHIVES OF DERMATOLOGICAL RESEARCH, 2011, 303 (08) : 563 - 572
  • [26] Sauchinone attenuates liver fibrosis and hepatic stellate cell through TGF-β/Smad signaling pathway
    Lee, Ju-Hee
    Jang, Eun Jeong
    Seo, Hye Lim
    Ku, Sae Kwang
    Lee, Jong Rok
    Shin, Soon Shik
    Park, Sun-Dong
    Kim, Sang Chan
    Kim, Young Woo
    CHEMICO-BIOLOGICAL INTERACTIONS, 2014, 224 : 58 - 67
  • [27] Dexamethasone attenuates bleomycin-induced lung fibrosis in mice through TGF-β, Smad3 and JAK-STAT pathway
    Shi, Keyun
    Jiang, Jianzhong
    Ma, Tieliang
    Xie, Jing
    Duan, Lirong
    Chen, Ruhua
    Song, Ping
    Yu, Zhixin
    Liu, Chao
    Zhu, Qin
    Zheng, Jinxu
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2014, 7 (09): : 2645 - 2650
  • [28] Cilomilast Ameliorates Renal Tubulointerstitial Fibrosis by Inhibiting the TGF-β1-Smad2/3 Signaling Pathway
    Xu, Man
    Li, Shumin
    Wang, Jiajia
    Huang, Songming
    Zhang, Aihua
    Zhang, Yue
    Gu, Wei
    Yu, Xiaowen
    Jia, Zhanjun
    FRONTIERS IN MEDICINE, 2021, 7
  • [29] Qishen granule attenuates cardiac fibrosis by regulating TGF-β /Smad3 and GSK-3β pathway
    Zeng, Zifan
    Wang, Qiyan
    Yang, Xiaomin
    Ren, Yinglu
    Jiao, Shihong
    Zhu, Qingqing
    Guo, Dongqing
    Xia, Kai
    Wang, Yong
    Li, Chun
    Wang, Wei
    PHYTOMEDICINE, 2019, 62
  • [30] Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway
    Zhang, Yin
    Lu, Yong-Bo
    Zhu, Wei-Jie
    Gong, Xiao-Xi
    Qian, Rui
    Lu, Yi-Jing
    Li, Yu
    Yao, Wei-Feng
    Bao, Bei-Hua
    Zhang, Yi
    Zhang, Li
    Cheng, Fang -Fang
    JOURNAL OF ETHNOPHARMACOLOGY, 2024, 324
12345