Hybrid Bladder Tumor: Urothelial Carcinoma With Squamous Cell Differentiation, Urothelial Sarcomatoid Carcinoma, and Concurrent Primary Mucinous Adenocarcinoma With Metastasis to the Penis

被引:1
|
作者
Antonov, Petar [1 ]
Raycheva, Gabriela [2 ]
Ivanov, Georgi [3 ]
Ivanov, Atanas
Uchikov, Petar [4 ]
Popov, Veselin [2 ]
Tzigarovski, Georgi [1 ]
Timev, Alexandar [5 ]
Grudeva, Zhanet [2 ]
机构
[1] Med Univ Plovdiv, Dept Urol & Gen Med, Plovdiv, Bulgaria
[2] Med Univ Plovdiv, Dept Clin Oncol, Plovdiv, Bulgaria
[3] Med Univ Plovdiv, Dept Gen & Clin Pathol, Plovdiv, Bulgaria
[4] Med Univ Plovdiv, Dept Special Surg, Plovdiv, Bulgaria
[5] Med Univ Sofia, Dept Urol, Sofia, Bulgaria
关键词
local recurrence of bladder cancer; muscle-invasive bladder cancer; bladder adenocarcinoma; penile; metastasis; hybrid bladder tumor; RADICAL CYSTECTOMY; URINARY-BLADDER; CANCER; RECURRENCE; FEATURES;
D O I
10.7759/cureus.68894
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The most common histological variants of bladder cancer include urothelial, squamous, and adenocarcinoma. In high-grade, invasive urothelial carcinoma, divergent differentiation can be observed, including glandular, squamous, trophoblastic, and small-cell types. Urothelial sarcomatoid carcinoma is characteristic of advanced carcinomas and is considered a possible common end route for all epithelial carcinomas. Adenocarcinoma of the bladder refers exclusively to true glandular carcinomas. Hybrid tumors are extremely rare and consist of more than one tumor type within the total tumor mass. Penile metastases are extremely uncommon, and there are no reported cases of metastatic adenocarcinoma of the bladder in the literature.
引用
收藏
页数:6
相关论文
共 50 条
  • [41] IS UROTHELIAL CARCINOMA WITH SARCOMATOID DIFFERENTIATION RESPONSIVE TO NEOADJUVANT CHEMOTHERAPY?
    Almassi, Nima
    Vertosick, Emily
    Sjoberg, Daniel
    Pietzak, Eugene
    Cha, Eugene
    Donahue, Timothy
    Al-Ahmadie, Hikmat
    Dalbagni, Guido
    Bochner, Bernard
    Goh, Alvin
    JOURNAL OF UROLOGY, 2020, 203 : E844 - E845
  • [42] Malignant Infiltration of the Penis From Urothelial Carcinoma of the Bladder
    Tong, Carmen
    Daskalakis, Nikolas
    Edwards, Daniel C.
    Cahn, David B.
    Belkoff, Laurence
    Geynisman, Daniel M.
    UROLOGY, 2017, 107 : 23 - 25
  • [43] Survival outcomes of urothelial carcinoma with squamous differentiation versus pure squamous cell carcinoma
    Lonati, C.
    Afferi, L.
    Baumeister, P.
    Minervini, A.
    Mari, A.
    Krajewski, W.
    Borghesi, M.
    Rink, M.
    Montorsi, F.
    Briganti, A.
    Hurle, R.
    Contieri, R.
    Umari, P.
    Klatte, T.
    Teoh, J. Y-C.
    Soria, F.
    Simeone, C.
    Zamboni, S.
    Roumiguie, M.
    Roupret, M.
    Masson-Lecomte, A.
    Einerhand, S. M. H.
    Mattei, A.
    Moschini, M.
    EUROPEAN UROLOGY, 2021, 79 : S1010 - S1011
  • [44] Microcystic urothelial carcinoma of the urinary bladder metastatic to the penis
    Sari, Aysegul
    Uyaroglu, Mehmet Ali
    Ermete, Murat
    Oder, Mehmet
    Girgin, Cengiz
    Dincer, Cetin
    PATHOLOGY & ONCOLOGY RESEARCH, 2007, 13 (02) : 170 - 173
  • [45] A Case of Urinary Bladder Urothelial Carcinoma with Squamous, Glandular, and Plasmacytoid Differentiation
    Makise, Naohiro
    Morikawa, Teppei
    Takeshima, Yuta
    Homma, Yukio
    Fukayama, Masashi
    CASE REPORTS IN ONCOLOGY, 2014, 7 (02): : 362 - 368
  • [46] ADVERSE ONCOLOGIC OUTCOMES OF SQUAMOUS CELL CARCINOMA OF BLADDER AS COMPARED TO UROTHELIAL CARCINOMA
    Kurteva, Teodora
    Schoenberg, Mark
    Rabbani, Farhang
    JOURNAL OF UROLOGY, 2015, 193 (04): : E805 - E805
  • [47] Comprehensive Assessment of Immuno-oncology Biomarkers in Adenocarcinoma, Urothelial Carcinoma, and Squamous-cell Carcinoma of the Bladder
    Necchi, Andrea
    Madison, Russell
    Raggi, Daniele
    Jacob, Joseph M.
    Bratslavsky, Gennady
    Shapiro, Oleg
    Elvin, Julia A.
    Vergilio, Jo-Anne
    Killian, Jonathan K.
    Ngo, Nhu
    Ramkissoon, Shakti
    Severson, Eric
    Hemmerich, Amanda C.
    Huang, Richard
    Ali, Siraj M.
    Chung, Jon H.
    Reddy, Prasanth
    Miller, Vincent A.
    Schrock, Alexa B.
    Gay, Laurie M.
    Alexander, Brian M.
    Grivas, Petros
    Ross, Jeffrey S.
    EUROPEAN UROLOGY, 2020, 77 (04) : 548 - 556
  • [48] Sarcomatoid urothelial carcinoma of the ureter with heterologous elements of chondrosarcoma and osteosarcoma, and concurrent divergent squamous differentiation: A rare case report
    Attia, Arsany
    Siriwardana, Amila
    Desai, Devang
    UROLOGY CASE REPORTS, 2021, 34
  • [49] Micropapillary urothelial carcinoma of the bladder: A clinicopathologic comparison with urothelial carcinoma with and without divergent differentiation
    Hou, J.
    Saab, J.
    Holder, D.
    Mansukhani, M.
    McKiernan, J.
    DeCastro, G.
    Harik, L.
    VIRCHOWS ARCHIV, 2012, 461 : S288 - S288
  • [50] Effects of Concurrent Chemoradiotherapy on the Metastasis and the Mesenchymal Transition of Bladder Urothelial Carcinoma Cells
    Pan, Yueh
    Hong, Ying Chui
    Hsiao, Chi-Hao
    Shih, Hung-Jen
    Huang, Sheng-Hsien
    Wu, Sheng-Chuan
    Chang, Chin-Pao
    Chiu, Shao-Chi
    Cho, Der-Yang
    Shih, Ping-Hsiao
    ANTICANCER RESEARCH, 2021, 41 (10) : 4957 - 4968