Epigenetic reprograming in ATM-deficient pancreatic cancer: targeting EZH2-mediated oncogenic traits

被引：0
|
作者：
Roger, Elodie
Harle, Anna
Perkhofer, Lukas
Hessmann, Elisabeth
Kleger, Alexander
Gout, Johann
机构：
来源：
CANCER RESEARCH | 2024年 / 84卷 / 17期
关键词：
D O I：
10.1158/1538-7445.PANCREATIC24-B088
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
B088
引用
收藏
页数：2
相关论文
共 50 条
  • [41] EZH2-Mediated microRNA-139-5p Regulates Epithelial-Mesenchymal Transition and Lymph Node Metastasis of Pancreatic Cancer
    Ma, Jin
    Zhang, Jun
    Weng, Yuan-Chi
    Wang, Jian-Cheng
    MOLECULES AND CELLS, 2018, 41 (09) : 868 - 880
  • [42] Response to 5FU therapy in colorectal cancer is affected by EZH2-mediated BcIX splicing
    Benderska, Natalya
    Gazouli, Maria
    Aravantinos, Gerasimos
    Hartmann, Arndt
    Schneider-Stock, Regine
    CANCER RESEARCH, 2016, 76
  • [43] N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer
    Dardenne, Etienne
    Beltran, Himisha
    Benelli, Matteo
    Gayvert, Kaitlyn
    Berger, Adeline
    Puca, Loredana
    Cyrta, Joanna
    Sboner, Andrea
    Noorzad, Zohal
    MacDonald, Theresa
    Cheung, Cynthia
    Yuen, Ka Shing
    Gao, Dong
    Chen, Yu
    Eilers, Martin
    Mosquera, Juan-Miguel
    Robinson, Brian D.
    Elemento, Olivier
    Rubin, Mark A.
    Demichelis, Francesca
    Rickman, David S.
    CANCER CELL, 2016, 30 (04) : 563 - 577
  • [44] Targeting EZH2-mediated methylation of histone 3 inhibits proliferation of pediatric acute monocytic leukemia cells in vitro
    Al-Ghabkari, Abdulhameed
    Narendran, Aru
    CANCER BIOLOGY & THERAPY, 2021, 22 (04) : 333 - 344
  • [45] EZH2-Mediated Epigenetic Suppression of GDF15 Predicts a Poor Prognosis and Regulates Cell Proliferation in Non-Small-Cell Lung Cancer
    Lu, Xiyi
    He, Xuezhi
    Su, Jun
    Wang, Jing
    Liu, Xinyin
    Xu, Kun
    De, Wei
    Zhang, Erbao
    Guo, Renhua
    Shi, Yuenian Eric
    MOLECULAR THERAPY-NUCLEIC ACIDS, 2018, 12 : 309 - 318
  • [46] EZH2-mediated lncRNA ABHD11-AS1 promoter regulates the progression of ovarian cancer by targeting miR-133a-3p
    Zhang, Wen
    Huang, Xin
    Shi, Jianguo
    ANTI-CANCER DRUGS, 2021, 32 (03) : 269 - 277
  • [47] EZH2-Mediated Epigenetic Suppression Of GDF15 Predicts a Poor Prognosis and Regulates Cell Proliferation in Non-Small Cell Lung Cancer
    Lu, X.
    Liu, X.
    Guo, R.
    JOURNAL OF THORACIC ONCOLOGY, 2018, 13 (10) : S691 - S691
  • [48] EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy
    Bao, Yi
    Oguz, Gokce
    Lee, Wee Chyan
    Lee, Puay Leng
    Ghosh, Kakaly
    Li, Jiayao
    Wang, Panpan
    Lobie, Peter E.
    Ehmsen, Sidse
    Ditzel, Henrik J.
    Wong, Andrea
    Tan, Ern Yu
    Lee, Soo Chin
    Yu, Qiang
    NATURE COMMUNICATIONS, 2020, 11 (01)
  • [49] Targeting EZH1/2: tackling epigenetic resistance advances cancer therapy
    Zaki, Ram Abou
    El-Osta, Assam
    MEDCOMM, 2025, 6 (01):
  • [50] Functional Characterization of EZH2β, a Newly Identified Epigenetic Oncogene for Pancreatic Cancer
    Grzenda, A.
    Lomberk, G.
    Svingen, P.
    Mathison, A.
    Calvo, E.
    Iovanna, J.
    Xiong, Y.
    Faubion, W.
    Urrutia, R.
    PANCREAS, 2012, 41 (08) : 1361 - 1361
12345