Epigenetic reprograming in ATM-deficient pancreatic cancer: targeting EZH2-mediated oncogenic traits

被引:0
|
作者
Roger, Elodie
Harle, Anna
Perkhofer, Lukas
Hessmann, Elisabeth
Kleger, Alexander
Gout, Johann
机构
关键词
D O I
10.1158/1538-7445.PANCREATIC24-B088
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
B088
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Susceptibility of ATM-deficient pancreatic cancer cells to radiation
    Ayars, Michael
    Eshleman, James
    Goggins, Michael
    CELL CYCLE, 2017, 16 (10) : 991 - 998
  • [2] Role of EZH2-Mediated Epigenetic Silencing in Hepatocellular Carcinoma
    Cheng, Alfred S.
    Wong, Nathalie
    Choy, Kwong W.
    Yu, Jun
    To, Ka Fai
    Sung, Joseph J.
    GASTROENTEROLOGY, 2009, 136 (05) : A127 - A127
  • [3] EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion
    Xiaoqing Yi
    Jianfeng Guo
    Jing Guo
    Si Sun
    Ping Yang
    Junjie Wang
    Yuan Li
    Lisha Xie
    Jing Cai
    Zehua Wang
    Scientific Reports, 7
  • [4] EZH2-mediated development of therapeutic resistance in cancer
    Kaur, Parminder
    Shankar, Eswar
    Gupta, Sanjay
    CANCER LETTERS, 2024, 586
  • [5] EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian cancer migration and invasion
    Yi, Xiaoqing
    Guo, Jianfeng
    Guo, Jing
    Sun, Si
    Yang, Ping
    Wang, Junjie
    Li, Yuan
    Xie, Lisha
    Cai, Jing
    Wang, Zehua
    SCIENTIFIC REPORTS, 2017, 7
  • [6] The EZH2 epigenetic factor orchestrates oncogenic properties in ATMdeficient pancreatic cancer
    Roger, Elodie
    Harle, Anna
    Gout, Johann
    Perkhofer, Lukas
    Hessmann, Elisabeth
    Kleger, Alexander
    CANCER RESEARCH, 2024, 84 (02)
  • [7] Novel insights of EZH2-mediated epigenetic modifications in degenerative musculoskeletal diseases
    Ma, Zetao
    Chen, Lei
    Wang, Yushun
    Zhang, Sheng
    Zheng, Jianrui
    Luo, Yuhong
    Wang, Chao
    Zeng, Hui
    Xue, Lixiang
    Tan, Zhen
    Wang, Deli
    AGEING RESEARCH REVIEWS, 2023, 90
  • [8] Inhibition of pancreatic cancer by targeting the epigenetic EZH2 complex.
    Lomberk, Gwen Alyce
    Mathison, Angela
    Missfeldt, Mckenna
    Salmonson, Ann
    Kossak, Sarah
    Buttar, Navtej
    Urrutia, Raul
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
  • [9] EZH2-mediated epigenetic suppression of SH3BGRL potently inhibits lung cancer progression
    Liu, Zhiping
    Xu, Wen
    Tan, Xiansheng
    Li, Chunhua
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 548 : 53 - 59
  • [10] Multiomics profiling reveals druggable tumor-stroma interactions in ATM-deficient pancreatic cancer
    Roger, Elodie
    Mummey, Hannah M.
    Zimmer, Eleni
    Ragg, Julia
    Lee, Yuna
    Gaulton, Kyle J.
    Beutel, Alica K.
    Halbrook, Christopher J.
    Perkhofer, Lukas
    Gout, Johann
    Kleger, Alexander
    CANCER RESEARCH, 2024, 84 (17)