A concise review on recent development of indole derivatives for anticancer activities

Indole heterocycles have been considered as noteworthy associated hybrids because of their diverse applications in organic synthesis, and coordination chemistry, as well as in the field of medicinal chemistry. Hence, numerous researchers around the globe have produced indole and its derivatives as objective motifs and exploited their biological activities. This review article intended to represent information about the synthesis, potential of the anticancer property, cytotoxicity, and level of clinical treatments, which could lay out the investigation to extend more effective indole-derived anticancer medicines. This insight also presents advanced synthetic analogs of indole derivatives and their anti-cancer activity. The literature report represented for the anticancer agents herein covers largely for the year 2014-2023.