Dual SGLT1 and SGLT2 inhibition: more than the sum of its parts

被引：1
|
作者：
Sanchez-Munoz, Enrique [1 ,2 ]
Requena-Ibanez, Juan Antonio [2 ]
Badimon, Juan Jose [1 ]
机构：
[1] Complejo Asistencial Univ Leon, Serv Cardiol, Leon, Spain
[2] Icahn Sch Med Mt Sinai, Mt Sinai Fuster Heart Hosp, Atherothrombosis Res Unit, New York, NY 10029 USA
来源：
REVISTA ESPANOLA DE CARDIOLOGIA | 2024年 / 77卷 / 07期
关键词：
D O I：
10.1016/j.rec.2024.01.011
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：510 / 514
页数：5
相关论文
共 50 条
  • [21] Comparison of SGLT1, SGLT2, and Dual Inhibitor Biological Activity in Treating Type 2 Diabetes Mellitus
    Azizogli, Abdul-Rahman
    Vitti, Michael R.
    Mishra, Richa
    Osorno, Laura
    Heffernan, Corey
    Kumar, Vivek A.
    ADVANCED THERAPEUTICS, 2023, 6 (12)
  • [22] Novel natural and synthetic inhibitors of solute carriers SGLT1 and SGLT2
    Oranje, Paul
    Gouka, Robin
    Burggraaff, Lindsey
    Vermeer, Mario
    Chalet, Clement
    Duchateau, Guus
    van der Pijl, Pieter
    Geldof, Marian
    de Roo, Niels
    Clauwaert, Fenja
    Vanpaeschen, Toon
    Nicolai, Johan
    de Bruyn, Tom
    Annaert, Pieter
    IJzerman, Adriaan P.
    van Westen, Gerard J. P.
    PHARMACOLOGY RESEARCH & PERSPECTIVES, 2019, 7 (04):
  • [23] First-in-Human Study of YG1699, an SGLT1 and SGLT2 Dual Transporter Inhibitor
    Li, Chenghai
    Li, Tong
    Lee, Frank
    Xu, Roger H.
    Wang, Helen
    DIABETES, 2020, 69
  • [24] A Review of the Potential Role of Sotagliflozin: A Dual SGLT2 and SGLT1 Inhibitor-in the Treatment of Heart Failure
    Tran, Bao Anh C.
    White, Raechel T.
    Bullers, Krystal
    Cornelio, Cyrille K.
    JOURNAL OF PHARMACY TECHNOLOGY, 2024, 40 (05) : 248 - 256
  • [25] Effect of Sotagliflozin, a Dual SGLT1 and SGLT2 Inhibitor, on Systolic Blood Pressure in Patients with Type 2 Diabetes
    Hardin, Marquette
    Davies, Michael
    Carroll, Amy
    Umpierrez, Guillermo
    CIRCULATION, 2024, 150
  • [26] Biophysical characteristics of the pig kidney Na+/glucose cotransporter SGLT2 reveal a common mechanism for SGLT1 and SGLT2
    Mackenzie, B
    Loo, DDF
    PanayotovaHeiermann, M
    Wright, EM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (51) : 32678 - 32683
  • [27] Dapagliflozin Selectively Inhibits Human SGLT2 Versus SGLT1, SMIT, SGLT4 and SGLT6
    Bellamine, Aouatef
    Uveges, Albert
    Thompson, Chris
    Xiao, Haiguang
    Abell, Lynn
    Mintier, Gabriel
    Whaley, Jean
    DIABETES, 2011, 60 : A271 - A271
  • [28] Molecular docking and dynamics simulation of Orthosiphon stamineus against SGLT1 and SGLT2
    Subbiah, Usha
    Ajith, Athira
    Subbiah, Harini Venkata
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 41 (23): : 13663 - 13678
  • [29] Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2
    Chiara Ghezzi
    Donald D. F. Loo
    Ernest M. Wright
    Diabetologia, 2018, 61 : 2087 - 2097
  • [30] Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2
    Ghezzi, Chiara
    Loo, Donald D. F.
    Wright, Ernest M.
    DIABETOLOGIA, 2018, 61 (10) : 2087 - 2097
12345