A critical role for palmitoylation in pyroptosis

被引:1
|
作者
Sun, Zhiqi [1 ,2 ]
Hornung, Veit [1 ,2 ]
机构
[1] Ludwig Maximilians Univ Munchen, Gene Ctr, Butenandtstr 1, D-81377 Munich, Germany
[2] Ludwig Maximilians Univ Munchen, Dept Biochem, Butenandtstr 1, D-81377 Munich, Germany
关键词
GASDERMIN D;
D O I
10.1016/j.molcel.2024.05.023
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Three recent publications by Du et al.,1 1 Balasubramanian et al.,2 2 and Zhang et al.3 3 identified palmitoylation on cysteine 191/192 in gasdermin D as a key determinant of gasdermin D membrane translocation and oligomerization, ensuring efficient plasma membrane permeabilization during pyroptosis.
引用
收藏
页码:2218 / 2220
页数:3
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