Ultrasound assisted solvent-free approach for the synthesis of 4-thiazolidinone derivatives

被引:0
|
作者
Wahan, Simranpreet K. [1 ]
Chawla, Pooja A. [2 ]
Kumar, Rupesh [1 ]
Tandon, Nitin [3 ]
Bhargava, Gaurav [1 ]
机构
[1] IK Gujral Punjab Tech Univ, Dept Chem Sci, Kapurthala, Punjab, India
[2] BFUHS Univ, Univ Inst Pharmaceut Sci & Res, Faridkot, India
[3] Lovely Profess Univ, Sch Chem Engn & Phys Sci, Phagwara, India
关键词
Mechanochemistry; solvent-free synthesis; acoustic vibrations; ultrasonic waves; 4-thiazolidinones; GREEN SYNTHESIS; HETEROCYCLES;
D O I
10.1080/17415993.2024.2395936
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An economical and environment-friendly protocol involving the use of ultrasonic vibrations was developed for the synthesis of a series of diaryl-4-thiazolidinones. The highlights of the developed approach are significant enhancement in the product yield, short reaction time, solvent-free, free of any toxic metal as a catalyst, cheaper synthetic methodological approach as well as non-formation of side-products. The developed approach is useful in terms of immense biological relevance of thiazolidines as well as the greener approach for cyclo-condensation of functionalized imines with thioglycolic acid. [GRAPHICS] .
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页数:9
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