Ongoing and future clinical trials of device therapies for patients with heart failure

被引:0
|
作者
Khalid, Subaina Naeem [1 ]
Mansoor, Taha [2 ]
Bilal, Muhammad Ibraiz [3 ]
Ijaz, Sardar Hassan [4 ]
Fudim, Marat [5 ,6 ]
Greene, Stephen J. [5 ,6 ]
Nambi, Vijay [7 ,8 ]
Virani, Salim S. [7 ,9 ,10 ]
Fonarow, Gregg C. [11 ]
Abramov, Dmitry [12 ]
Minhas, Abdul Mannan Khan [7 ]
机构
[1] SUNY Upstate Med Univ, Dept Internal Med, Syracuse, NY USA
[2] Western Michigan Univ, Homer Stryker MD Sch Med, Dept Internal Med, Kalamazoo, MI 26982 USA
[3] Allegheny Hlth Network, Dept Internal Med, Pittsburgh, PA USA
[4] Hartford Hosp, Div Cardiol, Hartford, CT USA
[5] Duke Univ, Duke Clin Res Inst, Sch Med, Durham, NC USA
[6] Duke Univ, Sch Med, Dept Med, Durham, NC USA
[7] Baylor Coll Med, Sect Cardiovasc Res, Houston, TX USA
[8] Michael E Debakey Vet Affair Med Ctr, Houston, TX USA
[9] Aga Khan Univ, Dept Med, Karachi, Pakistan
[10] Texas Heart Inst, Houston, TX USA
[11] David Geffen Sch Med UCLA, Dept Med, Div Cardiol, Los Angeles, CA USA
[12] Loma Linda Univ Hlth, Dept Med, Div Cardiol, Loma Linda, CA USA
关键词
Cardiac failure; Future; Clinical trials; MANAGEMENT; DEFIBRILLATOR; STATE;
D O I
10.1016/j.cpcardiol.2024.102805
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heart failure continues to pose a significant burden in terms of morbidity, mortality, and healthcare costs worldwide despite the implementation of guideline-directed medical therapy. Addressing this challenge and improving clinical outcomes for this patient population remains an urgent priority. Recognizing the limitations in current medical approaches and exploring strategies to overcome these limitations are crucial steps toward improving future outcomes. Various device-based interventions, such as Cardiac Resynchronization Therapy devices and Left Ventricular Assist Devices, have demonstrated notable benefits for individuals with heart failure. Our review is aimed at summarizing the ongoing research into new device therapies for heart failure, emphasizing their potential to overcome the current challenges in treatment. By utilizing Clinicaltrials.gov, an online repository, we conducted a comprehensive search for trials investigating emerging device therapies for patients dealing with heart failure.
引用
收藏
页数:13
相关论文
共 50 条
  • [31] The past, present and future of heart failure therapies
    Leslie, S. J.
    JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH, 2006, 36 (03): : 249 - 252
  • [32] Clinical and analytical considerations in the study of health status in device trials for heart failure
    Normand, SLT
    Rector, TS
    Neaton, JD
    Piña, IL
    Lazar, RM
    Proestel, SE
    Fleischer, DJ
    Cohn, JN
    Spertus, JA
    JOURNAL OF CARDIAC FAILURE, 2005, 11 (05) : 396 - 403
  • [33] A blistering new era for bullous pemphigoid: A scoping review of current therapies, ongoing clinical trials, and future directions
    Khalid, Subaina Naeem
    Khan, Zeest Ali
    Ali, Muhammad Hamza
    Almas, Talal
    Khedro, Tarek
    Nagarajan, Vikneswaran Raj
    ANNALS OF MEDICINE AND SURGERY, 2021, 70
  • [34] Do Women and Men Respond Similarly to Therapies in Contemporary Heart Failure Clinical Trials?
    Vaduganathan, Muthiah
    Tahhan, Ayman Samman
    Alrohaibani, Alaaeddin
    Greene, Stephen J.
    Fonarow, Gregg C.
    Vardeny, Orly
    Lindenfeld, JoAnn
    Jessup, Mariell
    Fiuzat, Mona
    O'Connor, Christopher M.
    Butler, Javed
    JACC-HEART FAILURE, 2019, 7 (03) : 267 - 271
  • [35] Digitalis in heart failure: declining use and ongoing outcome trials
    van Veldhuisen, Dirk J.
    Bauersachs, Johann
    EUROPEAN HEART JOURNAL, 2023, 44 (22) : 1976 - 1978
  • [36] Design Considerations for Clinical Trials of Autonomic Modulation Therapies Targeting Hypertension and Heart Failure
    Zannad, Faiez
    Stough, Wendy Gattis
    Mahfoud, Felix
    Bakris, George L.
    Kjeldsen, Sverre E.
    Kieval, Robert S.
    Haller, Hermann
    Yared, Nadim
    De Ferrari, Gaetano M.
    Pina, Ileana L.
    Stein, Kenneth
    Azizi, Michel
    HYPERTENSION, 2015, 65 (01) : 5 - 15
  • [37] PREDICTIVE VALUE OF SIX MINUTE WALK TEST IN HEART FAILURE PATIENTS: IMPLICATIONS FOR FUTURE CLINICAL TRIALS
    Rosero, Spencer
    Hernandez, Natalia
    Buber, Jonathan
    McNitt, Scott
    Polonsky, Bronislava
    Zareba, Wojciech
    Goldenberg, Ilan
    Kutyifa, Valentina
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2019, 73 (09) : 412 - 412
  • [38] Innovative devices for advanced heart failure: exploring the current state and future direction of device therapies
    Grinstein, Jonathan
    Burkhoff, Daniel
    CURRENT OPINION IN CARDIOLOGY, 2015, 30 (03) : 267 - 276
  • [39] Experimental Therapies and Ongoing Clinical Trials to Slow Down Progression of ADPKD
    Irazabal, Maria V.
    Torres, Vicente E.
    CURRENT HYPERTENSION REVIEWS, 2013, 9 (01) : 44 - 59
  • [40] Are subjects in heart failure trials similar to patients in clinical practice?
    Philbin, EF
    McCullough, PA
    Polanczyk, CA
    Jenkins, PL
    DiSalvo, TG
    CIRCULATION, 1998, 98 (17) : 866 - 866